MKKP Vol. 32 No. 2 (2016) Reviewer Acknowledgement [PDF]
, 2016 Sholeh, M. (Muhammad)
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Revisiting Akenfield: forty years of an iconic text [PDF]
, 2009 Ronald Blythe’s Akenfield, now forty years old, is generally acknowledged as one of the most influential books in the field of oral history. First published in 1969, Akenfield is a classic which still has the power to move the reader with its ...
Abrams, L.
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
[Review of] Russell Thornton, with C. Matthew Snipp and Nancy Breen. The Cherokees: A Population History [PDF]
, 1991 A first glance at the title might wrongly suggest that Thornton\u27s volume is best relegated to demography. This is, however, a wonderful reference for historians, ethnicists, and anthropologists, as well as an engaging work well suited for the general ...
Kasee, Cynthia R.
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
NIPS - Not Even Wrong? A Systematic Review of Empirically Complete Demonstrations of Algorithmic Effectiveness in the Machine Learning and Artificial Intelligence Literature [PDF]
, 2018 Objective: To determine the completeness of argumentative steps necessary to conclude effectiveness of an algorithm in a sample of current ML/AI supervised learning literature.
Király, Franz J +2 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Dying to be Seen: Snuff-Fiction's Problematic Fantasies of "Reality" [PDF]
, 2011 The mythic Snuff film has remained a persistent cinematic rumour since the mid-1970s. The discourses that surround Snuff are preoccupied by two factors: (a) the formal aesthetic, and (b) their alleged role as a kind of titillating pornography.
Jones, Steve
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