Results 111 to 120 of about 2,023,324 (272)

Review [PDF]

open access: yesJournal of South African Botany
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +11 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

How reliable are systematic reviews in empirical software engineering?

open access: yes, 2009
BACKGROUND – the systematic review is becoming a more commonly employed research instrument in empirical software engineering. Before undue reliance is placed on the outcomes of such reviews it would seem useful to consider the robustness of the ...
Kitchenham, BA   +10 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Academic Science News & Reviews December- January 1996-1997 [PDF]

open access: yes, 1996
https://commons.library.stonybrook.edu/academic-science-news-reviews/1002/thumbnail ...
Stony Brook University. Academic Science News & Reviews.
core  

Systematic reviews of diagnostic tests in cancer: review of methods and reporting

open access: yes, 2006
Objectives To assess the methods and reporting of systematic reviews of diagnostic tests. Data sources Systematic searches of Medline, Embase, and five other databases identified reviews of tests used in patients with cancer.
Hopewell, S   +20 more
core   +1 more source

Reviewing a reviewer☆ [PDF]

open access: yesEuropean Journal of Cardio-Thoracic Surgery, 2009
openaire   +2 more sources

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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