Results 181 to 190 of about 2,433,980 (262)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

A rapid and systematic review of the clinical effectiveness and cost-effectiveness of topotecan for ovarian cancer

Health Technology Assessment, 2001
C. Forbes, L. Shirran, A.-M. Bagnall, S. Duffy, G. ter Riet   +4 more
doaj   +1 more source

The GUIDE-CDSS framework: a comprehensive framework to GUIDE and evaluate the implementation of Clinical Decision Support Systems in healthcare, based on an overview of reviews. [PDF]

J Am Med Inform Assoc
Janssen ERC, Knoop J, Farabolini G, Baldini N, Hoogeboom T, Ceravolo MG, Negrini S, Kiekens C, PREPARE Project Group .   +8 more
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

A comparative study of DistilBERT and Perceiver for deceptive review detection in hospitality review data. [PDF]

Front Big Data
Remeş IX, Costea FM, Gyorödi CA.
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Addressing challenges in reviewing e-cigarette evidence: proposing a new 'Test for Dominance' in systematic reviews. [PDF]

J Public Health (Oxf)
Reid G, Nightingale G, Maani N, Smith M, Petticrew M.   +4 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Public health interventions for the prevention and management of overweight and obesity in children and adolescents: a rapid review. [PDF]

Front Public Health
Chandiok K, Kothari AB, Kulkarni B, Chowdhury R, Mummadi MK, Reddy SN, Gavaravarapu SM, Gonmei Z, Mukherjee A, Bansal PG.   +9 more
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source