Results 71 to 80 of about 8,814,223 (344)

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Advance care planning for adults with a progressive condition approaching end of life or loss of mental capacity: a systematic mapping review of the evidence

open access: yesHealth Services and Delivery Research, 2020
Background: Advance care planning (ACP) can be defined as a voluntary process of discussion about future care between an individual and their care providers, irrespective of discipline. An ACP discussion might include an individual’s concerns and wishes,
Sian Thomas   +3 more
doaj   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

The Impact of Human Factors on the Participation Decision of Reviewers in Modern Code Review [PDF]

open access: yesarXiv, 2018
Modern Code Review (MCR) plays a key role in software quality practices. In MCR process, a new patch (i.e., a set of code changes) is encouraged to be examined by reviewers in order to identify weaknesses in source code prior to an integration into main software repositories.
arxiv  

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side effects after major surgery: a systematic review

open access: yesHealth Technology Assessment, 2010
Objectives: To determine which class of non-opioid analgesics – paracetamol (acetaminophen), NSAIDs or COX-2 inhibitors – is the most effective at reducing morphine consumption and associated adverse effects when used as part of multimodal analgesia ...
Catriona McDaid   +5 more
doaj   +1 more source

REVIEWS [PDF]

open access: yesThe Journal of Theological Studies, 1915
n ...
openaire   +2 more sources

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

KardiaMobile 6L for measuring QT interval in people having antipsychotic medication to inform early value assessment: a systematic review

open access: yesHealth Technology Assessment
Background The indication for this assessment is the use of the KardiaMobile six-lead electrocardiogram device for the assessment of QT interval-based cardiac risk in service users prior to the initiation of, or for the monitoring of, antipsychotic ...
Marie Westwood   +3 more
doaj   +1 more source

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