Results 181 to 190 of about 11,067,918 (250)

Unveiling the Distinctive Brain Functional Dynamics Between Parkinson's Disease and Progressive Supranuclear Palsy

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Using hidden Markov models (HMM) to analyze dynamic brain states from resting‐state fMRI, this study identifies opposing temporal dynamics in Parkinson's disease (PD) and progressive supranuclear palsy (PSP). PD patients show reduced fractional occupancy in unimodal networks, while PSP patients exhibit increased occupancy and prolonged duration in ...
Chenfei Ye   +6 more
wiley   +1 more source

Advances in Targeting Central Cholinergic Dysfunction for Neurodegenerative Diseases: From Pharmacotherapy to Neuromodulation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
This review charts the evolution of cholinergic therapies for neurodegenerative diseases—from classical acetylcholinesterase inhibitors (AChEIs) providing symptomatic relief to precision multi‐target drugs and neuromodulation (VNS, DBS, NIBS) that restore dysfunctional circuits. Emerging gene therapy, cell regeneration, and advanced cholinergic imaging
Lei Lei   +4 more
wiley   +1 more source

Editorials: voices of a scientific journal. [PDF]

open access: yesCad Saude Publica
Alves LC, Lima LD, Carvalho MS.
europepmc   +1 more source

The Association Between Atherogenic Index of Plasma and Type 2 Diabetes Mellitus in a Multi‐Ethnic Population of Premature Coronary Artery Disease Patients: Insights From IPAD Study

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
In patients with premature coronary artery disease, higher atherogenic index of plasma was associated with prevalent type 2 diabetes and higher fasting blood sugar. Exploratory analyses suggested possible ethnicity‐related heterogeneity, while ROC analysis showed limited discrimination, supporting cautious interpretation rather than clinical screening ...
Reza Amani‐Beni   +8 more
wiley   +1 more source

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