Results 71 to 80 of about 2,788,561 (295)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Comments on DFT calculation, biological activity, anion sensing studies and crystal structure of (E)-4-chloro-2-((pyridin-2-ylimino)-methyl)phenol by Nuray Yıldırım, Neslihan Demir, Gökhan Alpaslan, Bahadir Boyacıoğlu, Mustafa Yıldız, and Huseyin Ünver, published in the Journal of the Serbian Chemical Society, volume 83, issue 6, 2018, pp. 707-721 [PDF]

Journal of the Serbian Chemical Society, 2019
The crystal structure of (E)-4-chloro-2-((pyridin-2-ylimino)-methyl)- phenol, recently published by Yıldırım et al. in J. Serb. Chem. Soc. 83 (2018) 707–721, is revised.
Rodić Marko V.
doaj   +1 more source

To revise or not to revise? This is the question

Annals of Operations Research
Abstract Buy and hold and periodical revisions are two competing investment strategies. Revising to the optimal one-period investment weights seemingly dominates the buy-and-hold strategy with random and uncontrolled investment weights determined by asset price changes.
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Comparison and System Development of a Two-Coil and Three-Coil Inductive Link for Transcutaneous Power Transfer

IEEE Access
Implantable electronic devices are powerful tools to alleviate a range of medical conditions. To minimize the risk of infections and increase patient comfort, no wires should penetrate the skin.
Maarten Schelles, Ward Lievens, Laurens Goyvaerts, Frederik Ceyssens, Rikky Muller, Michael Kraft   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Revision of metal-on-metal hip replacements with dual-mobility bearings and acetabular component retention

Bone & Joint Open
Aims: In metal-on-metal (MoM) hip arthroplasties and resurfacings, mechanically induced corrosion can lead to elevated serum metal ions, a local inflammatory response, and formation of pseudotumours, ultimately requiring revision. The size and diametral
William Fishley, Rajpal Nandra, Ian Carluke, Paul F. Partington, Mike R. Reed, Derek J. Kramer, Matthew J. Wilson, Matthew J. W. Hubble, Jonathan R. Howell, Sarah L. Whitehouse, Timothy G. Petheram, Al-Amin M. Kassam   +11 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Digital arthroplasty using double K-wire technique for hammertoe correction

Foot & Ankle Surgery: Techniques, Reports & Cases
Digital arthroplasty is a standard surgical treatment for hammertoe correction. To date, no study has been performed to evaluate a double K-wire technique for digital arthroplasty.
Dr. Kwanoo Lee, DPM, AACFAS, Dr. McKayla Seymour, DPM, AACFAS, Dr. Jonathon Srour, DPM, AACFAS, Dr. Israel Santander, DPM, AACFAS, Dr. Scott T. Vantre, DPM, FACFAS, Dr. Laurence G. Rubin, DPM, FACFAS   +5 more
doaj   +1 more source