Results 71 to 80 of about 948,667 (266)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Revision of metal-on-metal hip replacements with dual-mobility bearings and acetabular component retention

open access: yesBone & Joint Open
Aims: In metal-on-metal (MoM) hip arthroplasties and resurfacings, mechanically induced corrosion can lead to elevated serum metal ions, a local inflammatory response, and formation of pseudotumours, ultimately requiring revision. The size and diametral
William Fishley   +11 more
doaj   +1 more source

Revision by History

open access: yesJournal of Artificial Intelligence Research, 2015
This article proposes a solution to the problem of obtaining plausibility information, which is necessary to perform belief revision: given a sequence of revisions, together with their results, derive a possible initial order that has generated them; this is different from the usual assumption of starting from an all-equal initial order and modifying ...
openaire   +5 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Digital arthroplasty using double K-wire technique for hammertoe correction

open access: yesFoot & Ankle Surgery: Techniques, Reports & Cases
Digital arthroplasty is a standard surgical treatment for hammertoe correction. To date, no study has been performed to evaluate a double K-wire technique for digital arthroplasty.
Dr. Kwanoo Lee, DPM, AACFAS   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

The earliest Mesopsychidae and revision of the family Mesopanorpodidae (Mecoptera)

open access: yesZooKeys, 2011
The family Mesopanorpodidae is revised. Most taxa referred to this family are not related to the type genus Mesopanorpodes Tillyard, 1918. The type species of the latter, Mesopanorpodes wianamattensis, is closely related to Mesopsyche Tillyard, 1917 ...
Alexey Bashkuev
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Financial Audit and Spending of Appropriations

open access: yesEkonomski Vjesnik, 2013
Local and district (regional) governments receive various forms of revenue. The entitlement to and purpose of this income is determined by law. Likewise for companies owned by local government there are revenues with allocated use, which are also ...
Ivo Mijoč, Dubravka Mahaček
doaj  

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