Results 81 to 90 of about 948,667 (266)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Iterated AGM Revision Based on Probability Revision
Journal of Logic, Language and Information, 2023 AbstractClose connections between probability theory and the theory of belief change emerge if the codomain of probability functions is extended from the real-valued interval [0, 1] to a hyperreal interval with the same limits. Full beliefs are identified as propositions with a probability at most infinitesimally smaller than 1.
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
A Basis for AGM Revision in Bayesian Probability Revision
Journal of Philosophical Logic, 2023 AbstractIn standard Bayesian probability revision, the adoption of full beliefs (propositions with probability 1) is irreversible. Once an agent has full belief in a proposition, no subsequent revision can remove that belief. This is an unrealistic feature, and it also makes probability revision incompatible with belief change theory, which focuses on ...
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Parallel belief revision: Revising by sets of formulas
Artificial Intelligence, 2012 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
James P. Delgrande, Yi Jin 0006
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Effects of Two Different Bleaching Agents on the Microhardness of Composite
Pakistan Journal of Medicine and DentistryBackground: Various bleaching agents are used in different concentrations to overcome discoloration of teeth. The oxidizing nature of these bleaching agents can cause replacement of composite due to their negative physical and mechanical properties. The
Tahmeena Atiq +5 more
doaj +1 more source
Revised and edge revised Szeged indices of graphs
Ars Mathematica Contemporanea, 2013 The revised Szeged index is a molecular structure descriptor equal to the sum of products [ n u ( e ) + n 0 ( e ) / 2] × [ n v ( e ) + n 0 ( e ) / 2] over all edges e = u v of the molecular graph G , where n 0 ( e ) is the number of vertices equidistant from u and v , n u ( e ) is the number of vertices whose ...
Ashrafi, Ali Reza, Faghani, Morteza
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Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source