Results 51 to 60 of about 712,965 (355)
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
HUBUNGAN PRILAKU KEPEMIMPINAN KEPALA SEKOLAH DENGAN KINERJA GURU DI SMP NEGERI 2 KECAMATAN KETANGGUNGAN KABUPATEN BREBES [PDF]
, 2012 Oppgavens tema er revisors profesjonelle skepsis. Konseptet profesjonell skepsis spiller en nøkkelrolle for kvaliteten av revisjonen (Boyle & Carpenter, 2015).
Rudi, Silje H. G., Sandvik, Charlotte
core +1 more source
A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Publicadas nuevas recomendaciones de RCP y Soporte Vital: Conferencia ILCOR 2015
Revista Electrónica de AnestesiaR, 1970 El pasado día 15 de octubre de 2015 se han publicado, de forma simultánea en todo el mundo, las nuevas Recomendaciones de Resucitación Cardio-pulmonar (RCP) de 2015 auspiciadas por el International Liaison Committee on Resuscitation (ILCOR).
Fco. Javier García Vega +1 more
doaj +1 more source
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
El desarrollo del marco jurídico del revisor fiscal [PDF]
, 2014 Se hace necesario estudiar sus orígenes y la evolución jurídica que ha tenido en nuestra nación, a través de los avatares económicos de nuestro pueblo, permitiéndonos entenderlo en toda su dimensión, también se ha hecho necesario crear herramientas que ...
Sanabria Triana, Essenover
core
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source