Results 61 to 70 of about 723,158 (319)
Revised Estimates for the Number of Human and Bacteria Cells in the Body
bioRxiv, 2016 We critically revisit the “common knowledge” that bacteria outnumber human cells by a ratio of at least 10:1 in the human body. We found the total number of bacteria in the “reference man” to be 3.9·1013, with an uncertainty (SEM) of 25%, and a variation
R. Sender, Shai Fuchs, R. Milo
semanticscholar +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
A revised airway epithelial hierarchy includes CFTR-expressing ionocytes
Nature, 2018 The airways of the lung are the primary sites of disease in asthma and cystic fibrosis. Here we study the cellular composition and hierarchy of the mouse tracheal epithelium by single-cell RNA-sequencing (scRNA-seq) and in vivo lineage tracing.
Daniel T. Montoro +28 more
semanticscholar +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
La obligación del contador público de dar fe pública cuando el panorama del país está rodeado de fraude [PDF]
, 2013 Los fraudes económicos que se han presentando últimamente en Colombia nos llevan a preguntarnos ¿cuál es la responsabilidad de los profesionales de la contabilidad?
Hernández Parra, Gloria Janneth +1 more
core
Desmognathus quadramaculatus [PDF]
, 1974 Number of Pages: 4Integrative BiologyGeological ...
Valentine, Barry D.
core +1 more source
A revisão do texto literário: um trabalho de memória
Scripta, 2010 A partir da prática de revisão de uma variedade de textos, o artigo reflete sobre o pressuposto de que o texto literário, por sua especificidade, requer do revisor um domínio que extrapola o de um revisor de outras modalidades de textos.
Elzira Divina Perpétua +1 more
doaj
Panorama Económico, 1994 Es la función social por excelencia del Contador Público, cuando se desempeña . como Revisor Fiscal, como Auditor Externo, Consultor, Perito Contable, como Auxiliar de la Justicia, en fin, cuando tenga que dar testimonio en forma fide- digna de ...
Guillermo Quintana.Sossa
doaj +1 more source
Information Systems Frontiers, 2017 Based on a critical review of the Unified Theory of Acceptance and Use of Technology (UTAUT), this study first formalized an alternative theoretical model for explaining the acceptance and use of information system (IS) and information technology (IT ...
Yogesh Kumar Dwivedi +4 more
semanticscholar +1 more source