Results 51 to 60 of about 15,878 (284)

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu, Wanying Chen, Haijiang Qiu, Weihan Zheng, Ying Jiao, Jingheng Du, Zhudan Zhuang, Xing Hua, Jingyi Gu, Yuheng Liu, Zhaojin Li, Jingbin Xie, Hanxiao Sun, Huifei Lan, Xin Sun, Yunxia Xue, Ting Fu, Zhijie Li, Guobing Chen, Shiyu Li, Jun Liu   +20 more
wiley   +1 more source

Monitoring and evaluation system for revitalization programmes in Germany

Economics and Environment
Monitoring and evaluation should form the foundation of revitalisation programme management. The literature on the subject points to a general reluctance of municipalities to assess the effects of implemented revitalisation programmes, as well as the ...
Natalia Dziarmakowska
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Revitalisation of tourist destination [PDF]

, 2017
Novi izazovi, potrebe turista, snažna konkurencija na promjenjivom turističkom tržištu zahtijevaju od turističkih destinacija kontinuirano praćenje promjena i prema potrebi revitalizaciju.
Ćerimović, Ana
core   +1 more source

The Irish Language – a Unique Part of Irish Life and Cultural Revitalisation and Protection

Relacje Międzykulturowe, 2017
The present paper is devoted to the topic of the Irish language and its relation to Irish identity in the modern world, taking into account crucial aspects of the language’s revitalisation and protection.
Anna Slatinská
doaj   +1 more source

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

Advanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

Language Ideology within Shifting Political Ideology: A Critical Discourse Study of Taiwan’s Plans for Indigenous Language Revitalization

Critical Approaches to Discourse Analysis across Disciplines, 2019
Taiwan has 16 officially recognised Indigenous languages and all of them are endangered. Legislative efforts have been made to preserve these languages, but the results have not been fruitful.
Chien Ju Ting
doaj  

Explosive Valencia – futuristic imagination and the power of tradition in creating the image of urban spaces. Competition and conflict, or coexistence and praise of diversity?

Technical Transactions, 2020
Selected districts of Valencia and the gradual transformation of their image are presented in this article. The formulation of an appropriate strategy of action and the effect of an example that were initiated by the construction of the City of Arts and ...
Kaczmarska Elżbieta
doaj   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

People, Place and Partnership: Exploring Strategies to Revitalise Town Centres

European Spatial Research and Policy, 2017
More and more town centres in Western Europe are in decline, as indicated by growing shop vacancy rates in shopping streets. To turn the tide, decision makers look for revitalisation strategies. Are there any solutions? Making use of theoretical insights,
Gert-Jan Hospers
doaj   +1 more source