Results 51 to 60 of about 2,121,711 (340)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Three flavor revolution in fast pairwise neutrino conversion [PDF]
, 2021 Shashank Shalgar, Irene Tamborra
openalex +1 more source
The Scientific Revolution of Thomas Kuhn and Their Relevances for Humanization of Islamic Law [PDF]
, 2016 This paper tries to explore the views of Thomas Kuhn that science is moving through the stages that will culminate in normal conditions and then "rot" because it has been replaced by science or new paradigm. So next.
Kamal, M. A. (Muhamad)
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Gaseous Detector with Sub-keV Threshold to Study Neutrino Scattering at Low Recoil Energies
Advances in High Energy Physics, 2014 Gaseous detector with a sub-keV electron equivalent threshold is a very perspective tool for the precision measurement of the neutrino magnetic moment and for observing coherent scattering of neutrinos on nuclei.
A. V. Kopylov +3 more
doaj +1 more source
The Shelleys and the Idea of Europe [PDF]
, 2008 This article explores how the Shelleys and their circle configure ideas of “Europe” between January 1817 and March 1818. I begin with Frankenstein, discussing how Mary Shelley associates Frankenstein's experiment with the particularly “European” problem ...
Stock, Paul
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
China's Organic Revolution [PDF]
, 2007 Agriculture in China is at the onset of an Organic Revolution. From 2000 to 2006, China has moved from 45th to 2nd position in the world in number of hectares under organic management.
Paull, John
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source