Results 31 to 40 of about 443,344 (379)
Research published in this issue of Neuron from McGinty et al. (2016) suggests that attention may help bind information about value to specific options in economic choice. Responses of orbitofrontal neurons are strongly modulated by the distance from gaze to the position of a reward-predicting target.
Rei Akaishi, Benjamin Y. Hayden
openaire +3 more sources
The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs
GPR88 is an orphan G protein-coupled receptor (GPCR) considered as a promising therapeutic target for neuropsychiatric disorders; its pharmacology, however, remains scarcely understood.
Thibaut Laboute+12 more
doaj +1 more source
Gut microbes participate in food preference alterations during obesity
Hypothalamic regulations of food intake are altered during obesity. The dopaminergic mesocorticolimbic system, responsible for the hedonic response to food intake, is also affected. Gut microbes are other key players involved in obesity.
Alice de Wouters d’Oplinter+5 more
doaj +1 more source
Cerebellar modulation of the reward circuitry and social behavior
The cerebellum and reward-driven behavior Damage to the cerebellum manifests itself in various forms of cognitive impairment and abnormal social behavior. However, the exact role the cerebellum plays in these conditions is far from clear. Working in mice,
I. Carta+4 more
semanticscholar +1 more source
Automatic Reward Design via Learning Motivation-Consistent Intrinsic Rewards [PDF]
Reward design is a critical part of the application of reinforcement learning, the performance of which strongly depends on how well the reward signal frames the goal of the designer and how well the signal assesses progress in reaching that goal. In many cases, the extrinsic rewards provided by the environment (e.g., win or loss of a game) are very ...
arxiv
The Neuroscience of Drug Reward and Addiction.
Drug consumption is driven by a drug's pharmacological effects, which are experienced as rewarding, and is influenced by genetic, developmental, and psychosocial factors that mediate drug accessibility, norms, and social support systems or lack thereof ...
N. Volkow, M. Michaelides, R. Baler
semanticscholar +1 more source
Multi-Hop Knowledge Graph Reasoning with Reward Shaping [PDF]
Multi-hop reasoning is an effective approach for query answering (QA) over incomplete knowledge graphs (KGs). The problem can be formulated in a reinforcement learning (RL) setup, where a policy-based agent sequentially extends its inference path until ...
Xi Victoria Lin+2 more
semanticscholar +1 more source
It seemed to be good news when a company of worldwide fame started marketing cutting-edge medical devices. But, it has become disastrous now that all of the people responsible for patient safety have overlooked their duties. This is the story of Articular Surface Replacement (ASR) from Johnson & Johnson's DePuy Orthopaedics. The ASR was, at first, a
openaire +3 more sources
Stress and the dopaminergic reward system
Dopamine regulates reward-related behavior through the mesolimbic dopaminergic pathway. Stress affects dopamine levels and dopaminergic neuronal activity in the mesolimbic dopamine system.
J. Baik
semanticscholar +1 more source
Dynamics-Aware Comparison of Learned Reward Functions [PDF]
The ability to learn reward functions plays an important role in enabling the deployment of intelligent agents in the real world. However, comparing reward functions, for example as a means of evaluating reward learning methods, presents a challenge.
arxiv