Results 41 to 50 of about 1,393,287 (284)

The Shared Reward Dilemma [PDF]

, 2007
One of the most direct human mechanisms of promoting cooperation is rewarding it. We study the effect of sharing a reward among cooperators in the most stringent form of social dilemma, namely the Prisoner's Dilemma.
Cuesta, J. A., Jimenez, R., Lugo, H., Sanchez, A.   +3 more
core   +4 more sources

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Psychometric evaluation of the Chinese version of the Multidimensional Competitive Orientation Inventory

Scientific Reports
This study examined the psychometric properties of the Chinese version of the Multidimensional Competitive Orientation Inventory (Ch-MCOI) in adults from Mainland China.
Yuqian Wang, Gabor Orosz, Xi Chen, Chengguo Miao, Yansong Li   +4 more
doaj   +1 more source

Glucose-Sensing in the Reward System

Frontiers in Neuroscience, 2017
Glucose-sensing neurons are neurons that alter their activity in response to changes in extracellular glucose. These neurons, which are an important mechanism the brain uses to monitor changes in glycaemia, are present in the hypothalamus, where they ...
Laura L. Koekkoek, Laura L. Koekkoek, Laura L. Koekkoek, Joram D. Mul, Joram D. Mul, Joram D. Mul, Susanne E. la Fleur, Susanne E. la Fleur, Susanne E. la Fleur   +8 more
doaj   +1 more source

The Lateral Preoptic Area: A Novel Regulator of Reward Seeking and Neuronal Activity in the Ventral Tegmental Area

Frontiers in Neuroscience, 2020
The lateral preoptic area (LPO) is a hypothalamic region whose function has been largely unexplored. Its direct and indirect projections to the ventral tegmental area (VTA) suggest that the LPO could modulate the activity of the VTA and the reward ...
Adam G. Gordon-Fennell, Ryan G. Will, Ryan G. Will, Vorani Ramachandra, Lydia Gordon-Fennell, Juan M. Dominguez, Daniel S. Zahm, Michela Marinelli, Michela Marinelli, Michela Marinelli   +9 more
doaj   +1 more source

Reward Sensitivity at Age 13 Predicts the Future Course of Psychopathology Symptoms

Frontiers in Psychiatry, 2022
BackgroundThere are numerous observations of reward sensitivity being associated with different psychiatric disorders. Nonetheless, most studies investigating this relationship have been cross-sectional.
Raniere Dener Cardoso Melo, Robin N. Groen, Catharina A. Hartman   +2 more
doaj   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Increased Reward-Related Activation in the Ventral Striatum During Stress Exposure Associated With Positive Affect in the Daily Life of Young Adults With a Family History of Depression. Preliminary Findings

Frontiers in Psychiatry, 2021
Background: Being the offspring of a parent with major depression disorder (MDD) is a strong predictor for developing MDD. Blunted striatal responses to reward were identified in individuals with MDD and in asymptomatic individuals with family history of
Chantal Martin-Soelch, Matthias Guillod, Claudie Gaillard, Claudie Gaillard, Romina Evelyn Recabarren, Andrea Federspiel, Christoph Mueller-Pfeiffer, Philipp Homan, Philipp Homan, Philipp Homan, Gregor Hasler, Dominik Schoebi, Antje Horsch, Antje Horsch, Patrick Gomez   +14 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source