Results 71 to 80 of about 3,150,678 (298)
PROCESSING OF SMOKING AND MONETARY REWARDS AMONG CHRONIC SMOKERS: CHARACTERIZATION OF NEURAL RESPONSE, MODERATION BY ABSTINENCE, AND ASSOCIATION WITH SMOKING OUTCOMES [PDF]
, 2013 Theoretical models suggest that chronic smoking may be associated with both hypersensitivity to smoking and related cues and hyposensitivity to alternative reinforcers, and that these effects may be more pronounced during deprivation from smoking ...
Sweitzer, Maggie
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Real-reward testing for probabilistic processes
Theoretical Computer Science, 2014 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yuxin Deng 0001 +3 more
openaire +4 more sources
A correction term for the covariance of renewal-reward processes with multivariate rewards [PDF]
Statistics & Probability Letters, 2015 We consider a renewal-reward process with multivariate rewards. Such a process is constructed from an i.i.d.\ sequence of time periods, to each of which there is associated a multivariate reward vector. The rewards in each time period may depend on each other and on the period length, but not on the other time periods. Rewards are accumulated to form a
Patch, B., Nazarathy, Y., Taimre, T.
openaire +7 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2020 The current study is part of a larger project with the aim to investigate reward processing and pupillary responses in MDD. The current sample is a control group, where participants have no current MDD symptoms, but approximately one third has an history
Johan Lundin Kleberg, Mona Guath
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Reward processing in motivational and affective disorders. [PDF]
, 2016 Explores reward processing as a dimension spanning affective, addictive and psychotic disorders. The contributors draw on cognitive neuroscience, computational and experimental psychology theories and methods aligned to the Research Domains Criteria ...
Skandali, N +3 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Rare neural correlations implement robotic conditioning with reward delays and disturbances [PDF]
, 2013 Soltoggio A, Lemme A, Reinhart F, Steil JJ. Rare neural correlations implement robotic conditioning with reward delays and disturbances. Frontiers in Neurorobotics. 2013;7:6.Neural conditioning associates cues and actions with following rewards.
Lemme, Andre +15 more
core +1 more source