Results 91 to 100 of about 884,417 (275)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Data Science JournalOpen Science contributes to the collective building of scientific knowledge and societal progress. However, academic research currently fails to recognise and reward efforts to share research outputs.
Laurence Mabile +5 more
doaj +1 more source
’Blessed are the Dead Which Die in the Lord’: Andrew Fuller on the Beatific Vision
Perichoresis: The Theological Journal of Emanuel University, 2019 This essay examines the funeral sermon given by the Baptist theologian Andrew Fuller (1754–1815) for his friend and deacon Beeby Wallis in 1792 as a vantage-point from which to pursue reflection on Fuller’s concept of heaven and the beatific vision.
Haykin Michael A. G., Burns E. D.
doaj +1 more source
Bad News: An Experimental Study on the Informational Effects of Rewards [PDF]
Both psychologists and economists have argued that rewards often have hidden costs. One possible reason is that the principal may have incentives to offer higher rewards when she knows the task to be dificult.
Andrei Bremzeny +3 more
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Good science depends on good peer review
Ideas in Ecology and Evolution, 2015 I argue that the quality of both scientific research and how it is communicated is maintained and improved through a process analogous to Darwinian evolution.
Michael E. Hochberg
doaj
PROSPECTS FOR SHARIAH-COMPLIANT E-WALLET: ISSUES AND RECOMMENDATIONS
Malaysian Journal of Syariah and LawThe purpose of this study is to address the concept of e-wallet from a Sharīʿah perspective and its potential Sharīʿah concepts, issues, and challenges and to provide relevant recommendations to overcome those issues and challenges.
Abdul Muneem +4 more
doaj +1 more source
Antisocial pool rewarding does not deter public cooperation
, 2015 Rewarding cooperation is in many ways expected behaviour from social players. However, strategies that promote antisocial behaviour are also surprisingly common, not just in human societies, but also among eusocial insects and bacteria.
Perc, Matjaz, Szolnoki, Attila
core +2 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source