Results 71 to 80 of about 118,952 (268)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Unlocking rewards for sustainability: a framework for valuing pro-environmental behaviors in Polish cities

open access: yesSustainability: Science, Practice, & Policy
Addressing the pressing need for urban sustainability, we propose an innovative framework for quantifying and rewarding pro-environmental behaviors among urban residents.
Cristian Toșa   +6 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

The journey is the reward

open access: yesIndian Journal of Psychiatry, 2010
Byline: T. Sathyanarayana Rao You have achieved success in your field when you don't know whether what you're doing is work or play. Warren Beatty. Quoted in Deccan chronicle Bengaluru Edition, 19[sup] th Oct 2009 What a wonderful year it was! I have picked up the quote above simply because the exhilaration of many positives we had over shadowed all ...
openaire   +2 more sources

Role of HR Practices in Fostering Employee Creativity: Mediating Role of Organizational Culture

open access: yesJournal of Human Resource Management
Purpose – This paper explores the role of human resource (HR) practices in fostering employee creativity, specifically focusing on leadership, motivation, training, and rewards.
Saurav PANTA
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Critical analysis of drivers of employee engagement and their impact on job performance

open access: yesSA Journal of Human Resource Management
Orientation: This study examines the impact of drivers of employee engagement on job performance and investigates the relationship between employee engagement and job performance.
Mohammed Al-Haziazi
doaj   +1 more source

Home - About - Disclaimer - Privacy