Results 51 to 60 of about 118,952 (268)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Responsibility and Reward

open access: yesFinanzArchiv, 2003
A basic premise of optimal tax theory is that information about individuals productivity and time worked is unobservable and does not enter into the governments objective function. In this paper, we explore the implications of a framework where earning capacity both plays an intrinsic and an instrumental role.
Cappelen, Alexander W.   +1 more
openaire   +2 more sources

Role of Happiness When Evaluating Society

open access: yesEncyclopedia, 2022
Happiness, or life satisfaction, has become an important factor when considering what should be the objective of a society. Understanding the nature of happiness is thus important.
Bjørn Grinde
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Employees Demands For Remote, Online Work. Post Pandemic Changes [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2022
In the recent years, the labor market has undergone many changes in terms of work location, work program and work conditions. If until the pandemic caused by the SARS-CoV-2 virus, the classic option of working in the office was preferred among ...
Elena-Sabina Turnea
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Rewards and Recognition in Librarianship

open access: yesIn the Library with the Lead Pipe, 2013
Download this article as an EPUB for reading on mobile devices.   In Brief This article explores the professional award structure (formal and informal) of librarianship.
Micah Vandegrift
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The rewards of roughing it [PDF]

open access: yesScience, 2015
Modern life, concentrated in cities and lived online, is corroding many young people's innate love for nature. Much of science, too, is moving away from fieldwork. Biology is increasingly lab-based, and much important earth science research is now done in front of a computer screen rather than out in the physical world.
openaire   +2 more sources

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