Results 51 to 60 of about 49,127 (197)
Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease
The Journal of Physiology, EarlyView.Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.Melanie R. Bertossa, Jack R. T. Darby, Ashley S. Meakin, Mitchell C. Lock, Steven K. S. Cho, Christopher K. Macgowan, Mike. Seed, Michael D. Wiese, Janna L. Morrison +8 morewiley +1 more sourceTranslating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
The Journal of Physiology, EarlyView.Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi +18 morewiley +1 more sourceFaecal Microbiota Transplantation in Anorexia Nervosa: A Systematic Review of Methodologies, Outcomes, and Challenges With Recommendations for Future Studies
European Eating Disorders Review, Volume 34, Issue 4, Page 926-945, July 2026.ABSTRACT Objective
Anorexia nervosa (AN) is a severe psychiatric disorder displaying an altered gut microbiome. Faecal microbiome transplantation (FMT) has emerged as a powerful research tool and potential treatment option in AN due to the microbiome‐gut‐brain axis. Current studies are limited and reveal variable FMT protocols.Anna C. Thelen, Nele M. Korten, Larissa Blischke, Clara Voelz, Cordian Beyer, Jochen Seitz, Stefanie Trinh +6 morewiley +1 more sourceReye syndrome and liver transplantation
, 2010 Reye syndrome is a rare, but severe and often fatal disease. The etiology of the classical Reye syndrome is unknown, but it is typically preceded by a viral infection with a free interval of three to five days. The main physiopathological hypothesis is a Philippe Wolf, Anne-Catherine Saouli, Murat Cağ, Jacques Cinqualbre, Maxime Audet +4 morecore Legius syndrome in fourteen families
, 2010 Legius syndrome presents as an autosomal dominant condition characterized by café-au-lait macules with or without freckling and sometimes a Noonan-like appearance and/or learning difficulties.Denayer, E, Oostenbrink, R., Legius, E, Eric Legius, Van Minkelen, R, Lakeman, P, Rick Van Minkelen, Beert, E, Van Spaendonck-Zwarts, KY, Goede-Bolder, A. de, Peltonen, S., Van den Ouweland, AM, Spaendonck-Zwarts, KY, Brice, Glen, Ellen Denayer, Van den Ouweland, Ans Mw, Chmara, Magdalena, Bolder, A, de Goede, Arja, van Spaendonck, Karin Y., Peltonen, Sirkku, Mori, T., Rankin, J., van den Ouweland, Ans, Peltonen, S, Brice, G., Brice, G, Brems, H, Ouweland, A.M.W. van den, Van den Ouweland, Ans M. W., Rankin, Julia, Bever, Yolande, Brems, Hilde, Spaendonck-Zwarts, K.Y. van, Julia Rankin, Kievit, Anneke Maat, Oostenbrink, Rianne, Eline Beert, Karin Y Van Spaendonck-Zwarts, van Bever, Yolande, Keymolen, K., Anneke Maat Kievit, Kievit, A.M., Mangold, Elisabeth, Yolande van Bever, Lakeman, Phillis, Mori, T, Arja de Goede-Bolder, Ans MW Van den Ouweland, Ende, J. van der, Phillis Lakeman, Beert, E., Legius, E., Sirkku Peltonen, Keymolen, Kathelijn, Magdalena Chmara, van Bever, Y., van der Ende, J., Ishizaki, Takuma, van den Ouweland, Ans M.W., Mangold, E, Yoshimura, Akihiko, Van Minkelen, Rick, Beert, Eline, Keymolen, K, Legius, Eric, van Minckelen, Rick, van Minkelen, R., Ishizaki, T., Kievit, AM, Glen Brice, Rianne Oostenbrink, van Spaendonck-Zwarts, K.Y., de Goede-Bolder, A, Denayer, Ellen, Akihiko Yoshimura, Chmara, M., Yoshimura, A, Jenneke Van den Ende, van den Ouweland, A.M.W., Denayer, E., Van Spaendonck-Zwarts, Karin Y., Van den Ende, Jenneke, Lakeman, P., Mangold, E., de Goede-Bolder, A., van Bever, Y, Van den Ende, J, Yoshimura, A., de Goede-Bolder, Arja, Elisabeth Mangold, Takuma Ishizaki, Maat-Kievit, Anneke, Bever, Y. van, Oostenbrink, R, Hilde Brems, Maat Kievit, A, Mori, Tomoaki, Tomoaki Mori, Chmara, M, Kathelijn Keymolen, Minkelen, R. van, Rankin, J, Ishizaki, T +103 morecore +1 more sourceA first‐trimester mechanistic framework integrating three Physiopathologic biomarker domains for pre‐eclampsia classification
International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 182-191, July 2026.Abstract Objective
To develop and internally validate a mechanistic, three‐domain framework for early classification and prediction of pre‐eclampsia (PE) using first‐trimester angiogenic, uteroplacental, and maternal vascular biomarkers. Methods
In a prospective cohort of 1925 singleton pregnancies screened at 11 to 13.6 weeks, placental growth factor (Johnatan Torres‐Torres, Salvador Espino‐y‐Sosa, Raigam Jafet Martinez‐Portilla, Elsa Romelia Moreno‐Verduzco, Irma Eloisa Monroy‐Muñoz, Juan Mario Solis‐Paredes, Javier Perez Duran, Hector Borboa‐Olivares, Lourdes Rojas‐Zepeda +8 morewiley +1 more sourceLoss of the BMP antagonist, SMOC-1, causes Ophthalmo-Acromelic (Waardenburg Anophthalmia) syndrome in humans and mice [PDF]
, 2011 Ophthalmo-acromelic syndrome (OAS), also known as Waardenburg Anophthalmia syndrome, is defined by the combination of eye malformations, most commonly bilateral anophthalmia, with post-axial oligosyndactyly.Jackson, Ian J., Peter Branney, Rainger, Joe, Bardakjian, Tanya M, Sokhi, K., Pallotta, Rosanna, Koenig Rainer, Malcolm Fisher, McKie Lisa, Anita Wischmeijer, Fisher, M., Sérgio B. Sousa, Kishan Sokhi, Brunner, Han G, Mégarbané Andre, Fisher, Malcolm, Gillessen-Kaesbach, G., Sousa, Sérgio B., Bokhoven, J.H.L.M. van, Hennekam, Raoul C., Al-Gazali, L., Wischmeijer, Anita, FitzPatrick David R., Semerci, C. Nur, Andrea Superti Furga, Philippe Gautier, Ramos, Lina, Hennekam, Raoul, Bardakjian, T.M., Perry Paul, Semerci, C Nur, Pallotta Rosanna, van Beusekom Ellen, Ramos, L., Khan, Ayesha, Wieczorek, D, Lisa McKie, Ian J Jackson, Gillessen-Kaesbach Gabriele, Bicknell Louise, Saemah Zafar, Raoul Hennekam, Ferda Ozkinay, Elcioglu, Nursel, Fitzpatrick, David R, Adele S Schneider, Gillessen-Kaesbach, Gabriele Gertrud, Ramos Lina, Hennekam Raoul, Rosanna Pallotta, Lihadh Al-Gazali, Dagmar Wieczorek, Megarbane, A., Zafar, Saemah, van Bokhoven, H., Paul Perry, Rainer Koenig, Perry, P., Schneider, Adele S., Ian J. Jackson, Gautier Philippe, Semerci C. Nur, Gautier, P., C. Nur Semerci, Koenig, Rainer, Morrison, Harris, Gautier, Philippe, Bicknell, L., Al-Gazali Lihadh, Elcioglu Nursel, Saponari Anita, Furga, A.S., McKie, L., Han G Brunner, Ellen van Beusekom, Han G. Brunner, Sokhi Kishan, Zafar Saemah, Semerci, C.N., David Sexton, van Bokhoven, Hans, Gabriele Gillessen-Kaesbach, Sousa Sérgio B., Garavelli Livia, Ramsay, Jacqueline K, Lina Ramos, Schneider, Adele S, Ramsay Jacqueline K., Jackson Ian J., Rainger, J., Anita Saponari, FitzPatrick, D.R., Al-Gazali, Lihadh, Bicknell, Louise, Wieczorek, Dagmar, Elcioglu, N., Ayesha Khan, David R Fitzpatrick, Garavelli, Livia, Wieczorek, D., Jackson, Ian J, Sokhi, Kishan, Sexton, D., Jacqueline K Ramsay, Schneider, A.S., Harris Morrison, Adele S. Schneider, Hans van Bokhoven, Sexton David, Rainger Joe, Gillessen-Kaesbach, Gabriele, Beusekom, E. van, Furga, Andrea Superti, Brunner, Han G., Mégarbané, Andre, Wischmeijer, A., Wischmeijer Anita, Brunner, H.G., Tanya M Bardakjian, Pallotta, R., Hennekam, R., Branney Peter, Ozkinay, Ferda, Branney, Peter, Andre Mégarbané, Fisher Malcolm, Brunner Han G., FitzPatrick, David R., Morrison Harris, Bardakjian, Tanya M., Ozkinay, F., Khan, A., Sousa, S.B., Furga Andrea Superti, Jackson, I.J., Bokhoven, Hans van, David R. FitzPatrick, Özkınay, Ferda, Ozkinay Ferda, van Bokhoven Hans, Saponari, Anita, Jacqueline K. Ramsay, Garavelli, L., Tanya M. Bardakjian, Perry, Paul, Sexton, David, Nursel Elcioglu, Zafar, S., Bardakjian Tanya M., Khan Ayesha, Saponari, A., Branney, P., Sousa, Sérgio B, Sérgio B Sousa, van Beusekom, E., Louise Bicknell, Ramsay, Jacqueline K., Schneider Adele S., van Beusekom, Ellen, C Nur Semerci, Ramsay, J.K., Livia Garavelli, Wieczorek Dagmar, Joe Rainger, Beusekom, Ellen van, McKie, Lisa, Koenig, R., Morrison, H. +167 morecore +1 more source
