Results 161 to 170 of about 5,097,999 (301)

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu   +10 more
wiley   +1 more source

Development of an Atmospheric-Pressure Photoionization Source for VOC Detection With a Miniature High-Pressure Mass Spectrometer. [PDF]

open access: yesRapid Commun Mass Spectrom
Rowland AM   +6 more
europepmc   +1 more source

RF Ion Source

open access: yesOyo Buturi, 1969
OKAMOTO, Yukio, TAMAGAWA, Hajime
openaire   +1 more source

Characterization of the FEBIAD Ion Source for the INFN-SPES Facility

open access: yes, 2013
An intense research and development activity to finalize the design of the target ion source (TIS) system for the selective production of exotic species (SPES) facility (operating according to the isotope separation on line technique) is at present ...
ROSSIGNOLI, MASSIMO   +9 more
core  

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

open access: yesAdvanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan   +12 more
wiley   +1 more source

From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits

open access: yesAdvanced Science, EarlyView.
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang   +5 more
wiley   +1 more source

Characterization of an RF-Driven Plasma Ion Source for Heavy Ion Fusion

open access: yes, 2003
We are testing a high-current-density high-brightness Argon-Ion Source for Heavy Ion Fusion applications. The 100-kV 20-{micro}s source has produced up to 5 mA of Ar{sup +} in a single beamlet. The extraction current density is 100 mA/cm2.
Kwan, J W   +3 more
core  

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

open access: yesAdvanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang   +19 more
wiley   +1 more source

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