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Results 21 to 30 of about 63 (62)

ANGPT2 Drives Thyroid Cancer Progression Through PI3K/AKT Signaling and Correlates With Poor Prognosis and Immune Infiltration

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Angiopoietin‐2 (ANGPT2) is known to participate in tumor progression and immune modulation across multiple malignancies. Nevertheless, its expression pattern, prognostic value, and biological function in thyroid cancer (THCA) have not been comprehensively investigated.
Han Chen +5 more
wiley +1 more source

Neuroendocrine Carcinoma of the Head and Neck: A Two‐Decade Institutional Experience

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Primary neuroendocrine carcinoma (NEC) of the head and neck is rare (< 1% of cases) and aggressive, with poorly defined management strategies. This study evaluated clinical characteristics, treatment patterns, and survival outcomes in a single‐institution cohort, identifying factors associated with improved survival.
Micah K. Harris +11 more
wiley +1 more source

Kinetics of Antibody Responses and Effector Cell Sensitivity After High Dose Birch Extract Nasal Challenge

Allergy, EarlyView.
High‐dose birch‐extract nasal challenge induced synchronous peaks at 4 weeks in serum specific IgE (sIgE) and basophil sensitivity. Mast cell sensitivity via tSPT and sIgG1 and sIgG4 responses peaked later, at 6–8 weeks. Preseasonal allergen exposure attenuated seasonal sIgE increase and prevented further rise in tSPT sensitivity.
N. J. Campion +18 more
wiley +1 more source

Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper

Allergy, EarlyView.
ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg +18 more
wiley +1 more source

Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.
In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto +121 more
wiley +1 more source

Non‐Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy?

Head &Neck, Volume 48, Issue 9, Page 2541-2556, September 2026.
ABSTRACT Background In patients with locally advanced, non‐metastatic oropharyngeal squamous cell carcinoma (OPSCC), surgery‐based and nonsurgical treatment approaches have not been adequately compared in randomized Phase III clinical trials. Current clinical guidelines recommend various surgical and nonsurgical strategies across disease stages for ...
Primož Strojan +12 more
wiley +1 more source

Artificial Intelligence–Driven MRI for Cervical Nodal Metastasis Detection in Oral Squamous Cell Carcinoma: A Hierarchical Meta‐Analysis of Diagnostic Accuracy

Head &Neck, Volume 48, Issue 9, Page 2557-2569, September 2026.
ABSTRACT Background Artificial intelligence (AI) applied to magnetic resonance imaging (MRI) may improve detection of cervical lymph node metastases in oral squamous cell carcinoma (OSCC) but is heterogeneous. Methods A systematic review identified observational studies (from 2000) evaluating AI‐based MRI in adults with histopathologically confirmed ...
José Evando da Silva‐Filho +8 more
wiley +1 more source

Integrating Immunotherapy Into Head and Neck Surgery: Bridging Tumor Biology to Perioperative Decision‐Making, a Review

Head &Neck, Volume 48, Issue 9, Page 2570-2583, September 2026.
ABSTRACT Objective To provide a comprehensive review of the biological rationale, clinical evidence, and practical perioperative management of immunotherapy for the head and neck surgeon. Summary Background Data Standard treatment for resectable head and neck squamous cell carcinoma (HNSCC) has reached a survival plateau, with over 50% of patients ...
Nicholas Brian Shannon, Bruce Ashford
wiley +1 more source

Lateral Mucosal Flap With Steroid‐Eluting Implant in Revision Draf Type III Frontal Sinus Surgery

The Laryngoscope, Volume 136, Issue 9, Page 3732-3736, September 2026.
This technical note introduces a novel endoscopic strategy that integrates a laterally based endonasal mucosal flap with a bioabsorbable steroid‐eluting implant to prevent restenosis following revision of Draf type III frontal sinus surgery. The vascularized flap is stabilized and maintained in close apposition to the underlying bone by a self ...
Mario Turri‐Zanoni +6 more
wiley +1 more source

ARIA‐EAACI 2025: Person‐Centred, Digitally Enabled and Artificial Intelligence‐Assisted Change Management in Airway Diseases

Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.
ABSTRACT Allergic Rhinitis and its Impact on Asthma (ARIA) was, up until 2017, a guideline using the best evidence (Grading of Recommendations, Assessment, Development and Evaluation, GRADE) and developed as a change management strategy. A second change management strategy—in collaboration with the European Academy of Allergy and Clinical Immunology ...
Jean Bousquet +155 more
wiley +1 more source

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