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Conformationally-Constrained Alpha-RGIA Analogues
2023MCINTOSH JOSEPH MICHAEL +2 more
openaire +2 more sources
2010
Alpha-conotoxins Vc1.1 and RgIA are peptides from the venom of marine Conus snails that are currently in development as a treatment for neuropathic pain. We have reported previously that the alpha9alpha10 nicotinic acetylcholine receptor (nAChR) selective-conotoxins Vc1.1 and RgIA potently and selectively inhibit high voltage-activated (HVA) N-type ...
Callaghan, Brid, Adams, David J.
openaire +2 more sources
Alpha-conotoxins Vc1.1 and RgIA are peptides from the venom of marine Conus snails that are currently in development as a treatment for neuropathic pain. We have reported previously that the alpha9alpha10 nicotinic acetylcholine receptor (nAChR) selective-conotoxins Vc1.1 and RgIA potently and selectively inhibit high voltage-activated (HVA) N-type ...
Callaghan, Brid, Adams, David J.
openaire +2 more sources
CONFORMATIONALLY-CONSTRAINED α- -RGIA ANALOGUES
2021MCINTOSH JOSEPH MICHAEL +2 more
openaire +1 more source
Synthetic analgesic peptides of RgIA analogs
2021GAJEWIAK JOANNA, MCINTOSH J MICHAEL
openaire +1 more source
RgIA4 Accelerates Recovery from Paclitaxel-Induced Neuropathic Pain in Rats
Marine Drugs, 2020Kerry Lee Tucker +2 more
exaly
α-RgIA: A Novel Conotoxin That Specifically and Potently Blocks the α9α10 nAChR†,‡
Biochemistry, 2006J Michael McIntosh +2 more
exaly