Results 31 to 40 of about 29,693 (245)

Renal IGFBP6 Interacts With THBS1 to Drive Renal Cellular Senescence and Fibrosis

Advanced Science, EarlyView.
ABSTRACT Epithelial dedifferentiation and myofibroblast activation are critical drivers of chronic kidney disease (CKD) progression. Elevated levels of IGFBP6 have been linked to decreased renal function in CKD patients, but its precise role and underlying mechanisms remain unclear.
Ju‐tao Yu, Chang‐geng Xu, Xiao‐wei Hu, Run‐run Shan, Jia‐nan Wang, Xiang‐yu Li, Yu‐qing Wang, Yu‐hang Dong, Shen‐Zhuo‐Fan Huang, Shuai Sun, Tian Zhao, Ya‐Xin Ru, Xiao‐yu Shen, Rui Hou, Jian‐min You, Fei Zhang, Chao Li, Jie Wei, Chao Hou, Zhi‐juan Wang, Dan‐feng Zhang, Juan Jin, Jia‐gen Wen, Yu‐jie Liu, Ming‐ming Liu, Xiao‐ming Meng, Wei Wang   +26 more
wiley   +1 more source

Frequency of ABO and Rh Blood Groups in Gastro Esophageal Reflux Disease

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2011
BACKGROUND AND OBJECTIVE: Gastro esophageal reflux disease (GRED) is one of the most common digestive disorders. The relationship between H. Pylori infection and blood groups has been demonstrated.
M Sadreddini, Y Rasmi, T Maleki
doaj  

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Evaluation prevalence of Rh system major antigens (D, C, c, E, e) and their phenotypes in blood donors of Golestan province, Iran [PDF]

Medical Laboratory Journal
Background: The understanding of blood group phenotypes is currently limited to the ABO and Rh blood group systems. This study aimed to determine the frequency of Rh system antigens (D, C, c, E, e) and the phenotypes of the system in blood donors ...
Seyed Sadegh Baniaghil, Fardin Balochi, Alireza Ahmadi   +2 more
doaj  

MOLECULAR BASIS DETERMINATION OF D VARIANTS: NARRATIVE REVIEW

Hematology, Transfusion and Cell Therapy
Objective: The Rh blood group is one of the most complex blood groups known in humans, being is clinically relevant mainly due to the fact that antigens are highly immunogenic, responsible for a hemolytic transfusion reaction or on fetal RBCs.
ACS Castro, MOO Nascimento, MMP Luciano, JNV Silva, EJS Freitas, IPC Tavares, SRL Albuquerque, RS Leal, MS Gonçalves, JPM Neto   +9 more
doaj   +1 more source

Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity

Advanced Science, EarlyView.
Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau, Helen Broghammer, Claudia Gebhardt, Anne Hoffmann, Tobias Hagemann, Şeyma Midilli, Rachel S. Zimmer, Kristin Schubert, Vasiliki Karagiannakou, Anastasia Georgiadi, Mario Ost, Martin Krüger, Lisa Roth, Kerstin Krause, Nora Klöting, Maria Keller, Martin Wabitsch, Rima Nuwayhid, Roland H. Stimson, Michael Stumvoll, Matthias Blüher, Juliane Weiner, John T. Heiker   +22 more
wiley   +1 more source

Rh, Kell, Duffy, Kidd and Diego blood group system polymorphism in Brazilian Japanese descendants

, 2020
Polymorphisms of Rh, Kell, Duffy, Kidd and Diego blood group systems were studied in 209 unrelated Brazilian Japanese descendants from South of Brazil. The methods used were multiplex-PCR, AS–PCR and RFLP–PCR.
Melo, Fabiano Cavalcante de, Hashimoto, Margareth Naomi, Visentainer, Jeane Eliete Laguila, Flôres, Marli Aparecida Luvisuto Rossett, Sell, Ana Maria, Guelsin, Gláucia Andréia Soares, Fracasso, Adriana de Souza   +6 more
core   +2 more sources

Variability of blood parameters across ABO and Rh blood groups: Insights from a master health check-up data of adult population [PDF]

Medical Laboratory Journal
Background: The ABO and Rh blood group systems have been associated with variations in disease susceptibility. This study aimed to assess the variability in blood parameters, including red cell parameters and metabolic parameters (Renal function, hepatic
Joseph KI, Mohan Kumar, Kanagasabapathy Sivagami, Jeevithan Shanmugam, Periasamy Aparnavi   +4 more
doaj  

Causal‐Guided Ultra‐Long‐Term Time Series Forecasting Via Anticipated Covariates

Advanced Science, EarlyView.
Often treated as unknown, information from the future remains underutilized.We demonstrate that in a coupled dynamical system, providing the future state of the effect enables accurate forecasting of the cause for a long timesteps. A time series forecasting paradigm that introduces anticipated covariates to represent such known future states is ...
Jintong Zhao, Yufei Liu, Ruixi Huang, Zhongxue Gan, Siyang Leng   +4 more
wiley   +1 more source

Molecular – genetic variance of RH blood group system within human population of Bosnia and Herzegovina

, 2013
There are two major theories for inheritance of Rh blood group system: Fisher - Race theory and Wiener theory. Aim of this study was identifying frequency of RHDCE alleles in Bosnian - Herzegovinian population and ...
Elma Silajdžić, Lejla Pojskić, Lasić, Lejla, Rifat Hadžiselimović, Naris Pojskić, Lejla Lasić, Hadžiselimović, Rifat, Silajdžić, Elma, Naida Lojo-Kadrić, Pojskić, Naris, Lojo-Kadrić, Naida, Pojskić, Lejla   +11 more
core   +1 more source