Results 51 to 60 of about 118,582 (236)
Atrial Natriuretic Peptide Protects against Histamine-Induced Endothelial Barrier Dysfunction in Vivo [PDF]
, 2008 Endothelial barrier dysfunction is a hallmark of many severe pathologies, including sepsis or atherosclerosis. The cardiovascular hormone atrial natriuretic peptide (ANP) has increasingly been suggested to counteract endothelial leakage.
Bihari, Peter +9 more
core +1 more source
Arthritis &Rheumatology, Accepted Article.Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila +12 more
wiley +1 more source
Prolonged expression of the γ-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment [PDF]
, 2011 The normal tissue tolerance levels to fractionated radiotherapy have been appreciated by a century of careful clinical observations and radiobiological studies in animals.
Arlett, CF +4 more
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić +7 more
wiley +1 more source
Aspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer : a systematic review and overview of reviews [PDF]
, 2013 Background: Prophylactic aspirin has been considered to be beneficial in reducing the risks of heart disease and cancer. However, potential benefits must be balanced against the possible harm from side effects, such as bleeding and gastrointestinal (GI ...
Clarke, Aileen +9 more
core +1 more source
Clinical Advances in Periodontics, EarlyView.Abstract Background Autogenous grafts remain the gold standard for soft tissue augmentation, but allogeneic dermal matrices (ADMs) offer a viable alternative. Limited cellular infiltration and neovascularization restrict ADM efficacy; this study investigates a novel microsurfaced ADM (MS‐ADM) designed to address these limitations. Methods This 180‐day,
Michael K. McGuire +4 more
wiley +1 more source
International Journal of Cancer, EarlyView.Schematic overview of systemic and bone marrow‐specific adiposity in Hodgkin Lymphoma (HL). Body Mass Index was associated with bone marrow (BM) involvement, relapse, and mortality (1). In contrast, increased yellow marrow density was associated with poorer prognosis (2).
Andreia Matos +22 more
wiley +1 more source
Aerobic fitness impacts sympathoadrenal axis responses to concurrent challenges [PDF]
, 2017 The combination of mental and physical challenges can elicit exacerbated cardiorespiratory (CR) and catecholamine responses above that of a single challenge alone.
Acevedo, Edmund O. +4 more
core +3 more sources
International Journal of Cancer, EarlyView.Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim +22 more
wiley +1 more source
Exploratory studies of physiological components of motion sickness: Cardiopulmonary differences between high and low susceptibles [PDF]
A comprehensive examination of cardiovascular autonomic response to motion sickness was studied and whether differences in cardiopulmonary function exist in high and low susceptibility groups were determined.
Naifeh, K.
core +1 more source