Results 191 to 200 of about 264,301 (247)

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

Based on untargeted metabolomics and metagenomics: a study on the mechanism of Miao ethnomedicine <i>Zingiber mioga</i> (Thunb.) Rosc. in treating slow transit constipation. [PDF]

Front Microbiol
Du Y, Chen L, Zhang X, Zeng J, Hu C.
europepmc   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

Clinical Outcomes of Robotic-Assisted Gynecologic Surgery: A Single-Center 70-Case Series Experience. [PDF]

Cureus
Bhave P, Jain S, Zaidi KU, Gour R, Brahmne M, Chatterjee M, Mehta N, Thakur N.   +7 more
europepmc   +1 more source

Prevalence of ABO and Rh blood groups among individuals attending a tertiary care hospital in Nepal: a retrospective cross-sectional study. [PDF]

BMJ Open
Chand AB, Sen B, Khadka J, Pandey S, Nepal B.   +4 more
europepmc   +1 more source

Harnessing NIR-II-responsive Rh single-atom nanozymes for photothermal-catalytic immunomodulation and eradication of drug-resistant biofilms in deep tissues. [PDF]

Mater Today Bio
Mao B, Huang B, Li M, Zhang W, Chang Q, He X, Xu S.   +6 more
europepmc   +1 more source

Impact of left vs. right hemisphere stroke on driving: lateralized attention deficits and executive dysfunction linked to impaired driving. [PDF]

Front Stroke
Schendel K, Santavicca I, Herron TJ, Lwi SJ, Curran BC, Chok JM, Baldo J.   +6 more
europepmc   +1 more source

Phage Stability Across Conditions: Ensuring Accurate Use of Viral Surrogates in Antiviral Testing. [PDF]

Viruses
Poelzl S, Kittinger C.
europepmc   +1 more source