Results 271 to 280 of about 320,436 (348)

Value of ultra‐high‐field MRI in patients with drug‐resistant focal epilepsy and negative 3T MRI (EpiUltraStudy): Diagnostic gain of 7T structural analysis

Epilepsia, EarlyView.
Abstract Objective Resective epilepsy surgery is an evidence‐based treatment option for patients with focal drug‐resistant epilepsy (DRE). Seizure outcome after surgery is largely dependent on detection and delineation of an epileptogenic lesion on magnetic resonance imaging (MRI). However, detection fails in 30% of patients at 3 Tesla (T) MRI, thereby
Rick H. G. J. van Lanen, Daniel Uher, Christianne M. C. Hoeberigs, Paul A. M. Hofman, Remco Santegoeds, Christopher Wiggins, Desmond H. Y. Tse, Esther G. M. Steijvers, Jacobus F. A. Jansen, Gerald S. Drenthen, Alard Roebroeck, Dimo Ivanov, Benedikt A. Poser, Sander M. J. van Kuijk, Govert Hoogland, Kim Rijkers, Louis G. L. Wagner, Guido Widman, Jan Beckervordersandforth, Sylvia Klinkenberg, Rob P. W. Rouhl, Daniel Delev, Hans Clusmann, Stefan Wolking, Yvonne Weber, Laurien K. Dhaenens‐Meyer, Elisabeth Schriewer, Alfred Meurs, Katrien Jansen, Tom Theys, Wim van Paesschen, Dirk van Roost, Walter H. Backes, Albert J. Colon, Olaf E. M. G. Schijns, on behalf of the ACE Epilepsy Surgery group, Gwendolyn de Bruyn, Albert Colon, Jim Dings, Marc Hendriks, Danny Hilkman, Christianne Hoeberigs, Jochem van der Pol, Lotte de Jong, Kim Rijkers, Sylvia Klinkenberg, Vivianne van Kranen Mastenbroek, Jeske Nelissen, Pieter Kubben, Walter M. Palm, Rob P. W. Rouhl, Olaf Schijns, Simon Tousseyn, Marielle Vlooswijk, Louis Wagner, Dorien Weckhuysen, Ilse van Straaten   +56 more
wiley   +1 more source

Duodenal endoscopic submucosal dissection using dual-channel rapid hemostasis for a large tumor involving the papilla. [PDF]

Endoscopy
Nomura T, Kobayashi M, Yamada J, Kumazawa H, Isono Y, Mukai K.   +5 more
europepmc   +1 more source

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

Blood group profile of Türkiye with regional and demographic differences: a 23-year retrospective study. [PDF]

Turk J Med Sci
Sağdur L, Karaca A, Günçikan MN, Yilmaz M, Kinik K.   +4 more
europepmc   +1 more source

Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics

The FEBS Journal, EarlyView.
We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson, Isabel Fernandes Parreira, Ruth H. Thompson, Mark O. Collins, Jonathan G. Shaw, Luke R. Green   +5 more
wiley   +1 more source

Transient rapamycin treatment avoids unwanted host immune responses toward AAV-delivered anti-HIV antibodies. [PDF]

Nat Commun
Fuchs SP, Mondragon PG, Zabizhin R, Tomer S, Wang L, Cook E, Dudley DM, Weisgrau KL, Furlott J, Coonen J, Alexander E, Xie J, Gao G, Termini JM, Martinez-Navio JM, Zhen A, Desrosiers RC.   +16 more
europepmc   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Multifunctional Dynamic Hydrogel Based on a Micelle-Cross-Linked Chitosan Network for Infected Wound Healing. [PDF]

ACS Omega
Wang C, Wei P, Li B, Sun N.
europepmc   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

The FEBS Journal, EarlyView.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs, Remi Hatinguais, Mike de Kok, R. J. Eveline Li, Tesfay M. Godefa, Victor L. J. L. Thijssen, Yvette van Kooyk, Sandra J. van Vliet   +7 more
wiley   +1 more source

Co-delivery of spiramycin and curcumin nanoemulsions for treating acute (RH strain) and chronic (Tehran strain) toxoplasmosis in BALB/c mice. [PDF]

Parasitol Res
Hashemi-Hafshejani S, Amani A, Azami SJ, Valian HK, Mohebali M, Rampisheh Z, Shojaee S.   +6 more
europepmc   +1 more source