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Investigating myopathic causes of rhabdomyolysis [PDF]
, 2017 Rhabdomyolysis is an acute, and frequently severe, pathological event, characterized by rapid necrosis and destruction of striated muscle tissue. It is clinically characterized by muscle pain, weakness and emission of dark urine. The mechanisms that lead
Semplicini, Claudio
core
, 2012 Rhabdomyolysis is a clinical condition of potential life threatening destruction of skeletal muscle caused by diverse mechanisms including drugs and toxins.
Hohenegger, Martin
core +1 more source
Topics in Cognitive Science, EarlyView.Abstract Mushrooms are a ubiquitous and essential component in our biological environment and have been of interest to humans around the globe for millennia. Knowledge about mushrooms represents a prime example of cumulative culture, one of the key processes in human evolution.
Andrea Bender, Åge Oterhals
wiley +1 more source
Increased risk of rhabdomyolysis in patients using statins: a population-based case-control study
Therapeutic Advances in Drug SafetyBackground: Statins have been demonstrated to decrease cardiovascular events in high-risk patients. Statin-induced myotoxicity is a major contributor to statin intolerance and often the leading cause of statin discontinuation.
Ya-Wen Lu +3 more
doaj +1 more source
Veterinary Dermatology, EarlyView.Background: Oclacitinib is a Janus kinase inhibitor approved for the treatment of pruritus associated with allergic dermatitis in dogs and may be effective in horses. Objectives: To evaluate the efficacy of oclacitinib in reducing pruritus and skin lesions in horses with allergic dermatitis.
Nuttawut Nuchprayoon +6 more
wiley +1 more source
Case Reports in Medicine, 2018 Rhabdomyolysis is a potentially life-threatening clinical syndrome associated with muscle injury which can cause a leakage of intracellular contents, manifested from the range of being asymptomatic to a life-threatening condition causing acute kidney ...
Ami Amin +6 more
doaj +1 more source
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials
Experimental Physiology, EarlyView.Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler +2 more
wiley +1 more source
Rhabdomyolysis- Diagnosis and Treatment
, 2016 Rhabdomyolysis is the dissolution of skeletal muscle caused by injury to skeletal muscle. It is a direct result of leakage of toxic cellular content into the blood stream. The most common cause of rhabdomyolysis is drug use, trauma, immobility, medicines
Chifamba, Ngonidzashe
core
The Journal of Physiology, EarlyView.Abstract figure legend Schematic illustrating the in silico study pipeline. A total of 50,000 virtual myocytes were generated, which were then filtered to 7093 myocytes that fit experimentally constrained biomarkers for physiological electrical and calcium behaviour under wild‐type conditions.
Katherine Flannery +3 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 13, 15 July 2026.Simvastatin induces metabolic suppression, mitochondrial dysfunction, and atrophy‐related responses in skeletal muscle cells. In differentiated C2C12 myotubes, metformin partially attenuates these alterations by preserving myotube structural integrity, reducing cellular stress signaling, and maintaining mitochondrial network organization despite ...
Chuqi He +6 more
wiley +1 more source