Results 101 to 110 of about 35,187 (207)

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

An Extremely Rare Cause of Rhabdomyolysis: Emery Dreifuss Syndrome

Bagcilar Medical Bulletin
Intense physical activity, medications and trauma are common causes of rhabdomyolysis. However, etiologic factor of rhabdomyolysis can not be determined in a remarkable proportion of the cases.
Hazal Levent, Yunus Çoruk, Elif Itır Şen, Yasemin Çepni, Ayça Çınar, Ahmet Murat, Numan Görgülü   +6 more
doaj   +1 more source

Rhabdomyolysis in diabetic ketoacidosis.

, 2003
Rhabdomyolysis is a potentially lethal disorder, characterized by elevated serum concentrations of creatine kinase (CK) due to skeletal muscle injury.
Casteels, Kristina, Beckers, Dominique, Van Geet, Chris, Wouters, Carine   +3 more
core   +1 more source

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3513-3526, October 2026.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

Rhabdomyolysis-Induced Acute Kidney Injury in Diabetic Emergency: Underdiagnosed and an Important Association to Be Aware of

Case Reports in Medicine, 2018
Rhabdomyolysis is a potentially life-threatening clinical syndrome associated with muscle injury which can cause a leakage of intracellular contents, manifested from the range of being asymptomatic to a life-threatening condition causing acute kidney ...
Ami Amin, Bhavika Gandhi, Steven Torre, Alireza Amirpour, Jennifer Cheng, Mayurkumar Patel, Mohammad A. Hossain   +6 more
doaj   +1 more source

A Case Series of Sudden Death in Children Aged 12 Months to 4 Years From LPIN1 Deficiency and PPA2 Deficiency in Queensland

Journal of Paediatrics and Child Health, EarlyView.
Sophie Manoy, Sally Smith, Marita Smith, Catherine Atthow, Janette Spicer, Matthew Lynch, Michelle Lipke, Julie A. McEniery, David Coman, Anita Inwood, Jim McGill, Carolyn Bursle   +11 more
wiley   +1 more source

Ethylene Glycol Poisoning Without Fomepizole in a Regional Australian Intensive Care Unit: The Lactate Gap as the Diagnostic Key and the Consequences of Nasogastric Ethanol Therapy

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 62‐year‐old man presented comatose with pH 6.88 and no ingestion history. A point‐of‐care lactate above 31 mmol/L with a laboratory lactate of 0.8 mmol/L revealed a lactate gap, diagnosing ethylene glycol poisoning despite a near‐normal osmolar gap. High‐dose continuous renal replacement therapy corrected the acidosis; he survived.
Jacob Athans, Prashant Maan
wiley   +1 more source

Rhabdomyolysis in a recreational swimmer.

, 2012
Rhabdomyolysis is a clinical and biochemical syndrome resulting from skeletal muscle injury, which may ultimately lead to acute renal failure (ARF) and death. Exertional rhabdomyolysis refers to skeletal muscle injury that is usually induced by strenuous
Shariff, A.H., Stella, J.J.
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The Real‐World Safety Profile of Haloperidol: A Comprehensive Pharmacovigilance Analysis Using the Large‐Scale FAERS Database

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This first comprehensive FAERS‐based pharmacovigilance analysis of haloperidol over two decades characterized the real‐world safety profile across 9916 reports. Strong signals were found for nervous, psychiatric, and cardiac disorders. Known risks were confirmed and novel signals revealed. Sex‐ and age‐specific vulnerabilities were identified. Findings
Nengping Luo, Lu Xiao, Ying Liu, Xiang Liu   +3 more
wiley   +1 more source

Rhabdomyolysis : what wildland firefighters need to know. [PDF]

Rhabdomyolysis : what wildland firefighters need to know.Rhabdomyolysis (often called rhabdo) is a medical condition resulting from the breakdown of damaged muscle tissue.

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