Results 101 to 110 of about 63,641 (278)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Rhabdomyolysis in COVID-19: Report of Four Cases

Cureus, 2020
Coronavirus disease 2019 (COVID-19) is a global public health emergency. COVID-19 is most well known for affecting the respiratory system, although it can also result in several extrapulmonary manifestations.
Balraj Singh, Parminder Kaur, A. Mechineni, M. Maroules   +3 more
semanticscholar   +1 more source

The Molecular Diagnosis of Myopathies: Integrating Genomic, Proteomic, and Pathological Insights Toward Precision Medicine

Clinical Genetics, EarlyView.
Advances in genomic, proteomic, and transcriptomic technologies are transforming the diagnosis of genetic myopathies. When integrated with traditional muscle pathology, multi‐omics approaches improve diagnostic yield, clarify disease mechanisms, and support more precise, mechanism‐based therapeutic strategies for patients with neuromuscular disorders ...
Ludmila Alem, Denise de Abreu Pereira, Katia Carneiro   +2 more
wiley   +1 more source

Evaluation of atypical antipsychotics associated rhabdomyolysis using the FDA adverse event reporting system database

Scientific Reports
Rhabdomyolysis is a potentially fatal adverse reaction mainly caused by certain medications. Few real-world studies have shown a clear association between atypical antipsychotics and rhabdomyolysis.
Yi Yin, Jie Jiang, Youpeng Jin
doaj   +1 more source

Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats.

PLoS ONE, 2016
Overt systemic inflammatory response is a predisposing mechanism for infection-induced skeletal muscle damage and rhabdomyolysis. Aberrant DNA methylation plays a crucial role in the pathophysiology of excessive inflammatory response.
Chih-Chin Shih, Hiong-Ping Hii, Cheng-Ming Tsao, Shiu-Jen Chen, Shuk-Man Ka, Mei-Hui Liao, Chin-Chen Wu   +6 more
doaj   +1 more source

Acute renal failure due to rhabdomyolysis following a seizure

Journal of Family Medicine and Primary Care, 2013
Acute renal failure, oliguric or nonoliguric, is the most common complication of rhabdomyolysis. Rhabdomyolysis should be suspected in patients presenting with states of increased muscular activity, such as seizures, agitation, strenuous muscle exercise,
Ajay Mishra, Nikhil Dave
doaj   +1 more source

A forage-only diet alters the metabolic response of horses in training [PDF]

, 2012
Most athletic horses are fed a high-starch diet despite the risk of health problems. Replacing starch concentrate with high-energy forage would alleviate these health problems, but could result in a shift in major substrates for muscle energy supply from
A. Jansson, Connysson, Connysson, Danielsen, Devlin, Ellis, Essén-Gustavsson, Essén-Gustavsson, Farris, Geor, Gillham, Glade, Harris, Hintz, Houpt, Hudson, Hyyppä, J.E. Lindberg, Kelso, Lacombe, Lacombe, Lawrence, Lindholm, Lowry, Luthersson, MacLeay, Meyer, Muhonen, Pagan, Palmgren-Karlsson, Palmgren-Karlsson, Persson, Potter, Ragnarsson, Redbo, Schuback, Snow, Tinker, Voiton, Waller, Waller, Waters, Willard, Williamson, Willing, Wilson   +45 more
core   +2 more sources

Rhabdomyolysis as a manifestation of a severe case of COVID-19: A case report

Radiology Case Reports, 2020
Since the outbreak of the ongoing pandemic of the novel coronavirus disease (COVID-19) in Wuhan, China, from December 2019, we have learned that multiple organs can be affected with the potential for various complications.
Rola Husain, I. Corcuera‐Solano, E. Dayan, A. Jacobi, Mingqian Huang   +4 more
semanticscholar   +1 more source

S3 guideline diagnostics and therapy in alopecia areata – Part 2: Therapy, psychosocial and cosmetic support

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary This second part of the S3 guideline on the diagnosis and treatment of alopecia areata (AA), presents key recommendations on topical and systemic therapy, quality of life and support services. The first part of the guideline, published separately, covers the definition and content of epidemiology and diagnosis as well as comorbidities, risk and
Ulrike Blume‐Peytavi, Andria Constantinou, Tsenka Tomova‐Simitchieva, Adrian Tanew, Michael Sticherling, Hermann Girschick, Annika Vogt, Uwe Schwichtenberg, Uwe Gieler, André Märtens, Kerstin Zienert, Claudia Stenders, Ricardo Niklas Werner, Doris Wilborn   +13 more
wiley   +1 more source

Delayed presentation of severe rhabdomyolysis leading to acute kidney injury following atorvastatin-gemfibrozil combination therapy: a case report

Journal of Medical Case Reports, 2018
Background Rhabdomyolysis is a rare but serious complication of lipid-lowering therapy. Statin and fibrate combination increases the risk of rhabdomyolysis possibly by pharmacodynamic interactions.
Chamara Dalugama, Manoji Pathirage, S. A. M. Kularatne   +2 more
doaj   +1 more source