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Pediatric Rhabdomyolysis

Pediatrics In Review, 2020
Pediatric rhabdomyolysis is a common diagnosis that pediatricians need to be able to recognize because prompt treatment can prevent potential complications, such as acute kidney injury. The triggers for rhabdomyolysis are extensive, with viruses being the most common cause in pediatric patients.
Heidi Szugye
openaire   +3 more sources

Rhabdomyolysis and statins: A pharmacovigilance comparative study between statins

British Journal of Clinical Pharmacology, 2023
Rhabdomyolysis is a serious adverse drug reaction of statins. There are few studies comparing the risk of rhabdomyolysis between the different statins. Using the WHO pharmacovigilance database, VigiBase®, we compared the risk of rhabdomyolysis reporting ...
J. Montastruc
semanticscholar   +1 more source

Rhabdomyolysis

British Journal of Hospital Medicine, 2012
Rhabdomyolysis is the destruction of a significant amount of striated muscle, leading to disruptions in fluid balance, electrolytes and renal function. It may have either traumatic (such as crush injury) or non-traumatic causes. Diagnosis is typically made through the timely determination of the serum creatine kinase activity in a patient with a ...
Scott D. Bieber, J. Ashley Jefferson
  +7 more sources

Rhabdomyolysis

Orthopaedic Nursing, 2005
Rhabdomyolysis is the dissolution of skeletal muscle. Breakdown of the myocyte causes the extravasation of intracellular constituents, leading to a clinical syndrome--the classic triad of brown urine, muscle pain, and weakness. The pathogenesis of rhabdomyolysis is presented.
D, Singh, V, Chander, K, Chopra
openaire   +4 more sources

The Value of Lactate Dehydrogenase in Predicting Rhabdomyolysis-Induced Acute Renal Failure; a Narrative Review

Archives of Academic Emergency Medicine, 2021
Introduction: Determining the diagnostic value of available biomarkers in predicting rhabdomyolysis-induced acute kidney injury (AKI) is a priority. This study aimed to review the current evidence about the value of lactate dehydrogenase (LDH) in this ...
Hazhir Heidari Beigvand   +3 more
semanticscholar   +1 more source

Rhabdomyolysis

Chest, 2013
Rhabdomyolysis is a well-known clinical syndrome of muscle injury associated with myoglobinuria, electrolyte abnormalities, and often acute kidney injury (AKI). The pathophysiology involves injury to the myocyte membrane and/or altered energy production that results in increased intracellular calcium concentrations and initiation of destructive ...
Janice L, Zimmerman, Michael C, Shen
openaire   +2 more sources

RYR1-related rhabdomyolysis: a spectrum of hypermetabolic states due to ryanodine receptor dysfunction.

Current pharmaceutical design, 2021
Variants in the ryanodine receptor-1 gene (RYR1) have been associated with a wide range of neuromuscular conditions, including various congenital myopathies and malignant hyperthermia (MH).
N. Kruijt   +8 more
semanticscholar   +1 more source

RHABDOMYOLYSIS

Critical Care Clinics, 1999
Dissolution of the skeletal muscle, resulting in extravasation of the intracellular toxic metabolites into the circulatory system, and the accompanying manifestations, constitutes the clinical syndrome of rhabdomyolysis. The most frequent complication of this syndrome is acute renal failure, and its most life threatening side effects are hyperkalemia ...
P, Visweswaran, J, Guntupalli
openaire   +2 more sources

Tularemia and Rhabdomyolysis [PDF]

open access: possibleJAMA: The Journal of the American Medical Association, 1985
Rhabdomyolysis as a complication of tularemia occurred in four patients in Tennessee over a four-year period. All patients were severely ill and had renal failure. Tularemia was not suspected initially in any of these patients. One patient died of complications of rhabdomyolysis.
Richard E. Parrish   +6 more
openaire   +2 more sources

Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis‐mediated cell death

The FASEB Journal, 2019
Acute kidney injury is a common complication of rhabdomyolysis. A better understanding of this syndrome may be useful to identify novel therapeutic targets because there is no specific treatment so far.
Melania Guerrero-Hue   +14 more
semanticscholar   +1 more source

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