Results 11 to 20 of about 99,358 (330)

Relapsed Rhabdomyosarcoma [PDF]

Journal of Clinical Medicine, 2021
Relapsed rhabdomyosarcoma (RMS) represents a significant therapeutic challenge. Nearly one-third of patients diagnosed with localized RMS and over two-thirds of patients with metastatic RMS will experience disease recurrence following primary treatment, generally within three years.
Christine M. Heske, Leo Mascarenhas
openaire   +3 more sources

Circ-ZNF609 regulates G1-S progression in rhabdomyosarcoma [PDF]

Oncogene, 2019
Circular RNAs (circRNAs) represent a class of covalently closed RNAs, derived from non-canonical splicing events, which are expressed in all eukaryotes and often conserved among different species.
Bozzoni, Irene, Colantoni, Alessio, Dattilo, Dario, DI TIMOTEO, Gaia, Dominici, Carlo, Legnini, Ivano, Megiorni, Francesca, Morlando, Mariangela, Rossi, Francesca, Santini, Tiziana   +9 more
core   +2 more sources

Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population [PDF]

Molecular Cancer, 2016
The identification of signaling pathways that affect the cancer stem-like phenotype may provide insights into therapeutic targets for combating embryonal rhabdomyosarcoma.
Ciccarelli, Carmela, DI PAOLO, Virginia, Giampaolo, Adele, Gravina, GIOVANNI LUCA, Hassan, Hamisa Jane, Macioce, Giampiero, Marampon, Francesco, Milazzo, Luisa, Tombolini, Vincenzo, Vulcano, Francesca, Zani, Bianca Maria   +10 more
core   +10 more sources

Rhabdomyosarcoma: Current Therapy, Challenges, and Future Approaches to Treatment Strategies

Cancers, 2023
Simple Summary Rhabdomyosarcoma (RMS) is a rare pediatric sarcoma affecting skeletal muscle in children and young adults. It is responsible for 3% of all childhood malignant tumors and is the third most prevalent pediatric extracranial solid tumor ...
Ali Zarrabi, David Perrin, Mahboubeh Kavoosi, Micah Sommer, Serap Sezen, P. Mehrbod, Bhavya Bhushan, Filip Machaj, Jakub Rosik, Philip Kawalec, Saba Afifi, Seyed Mohammadreza Bolandi, Peiman Koleini, M. Taheri, T. Madrakian, Marek J Łos, Benjamin Lindsey, Nilüfer Çakır, Atefeh Zarepour, K. Hushmandi, Ali Fallah, Bahattin Koç, Arezoo Khosravi, M. Ahmadi, Susan Logue, G. Orive, Stevan Pecić, Joseph W. Gordon, S. Ghavami   +28 more
semanticscholar   +1 more source

The m6A reader YTHDC1 and the RNA helicase DDX5 control the production of rhabdomyosarcoma-enriched circRNAs

Nature Communications, 2023
N6-Methyladenosine (m^6A) is well-known for controlling different processes of linear RNA metabolism. Conversely, its role in the biogenesis and function of circular RNAs (circRNAs) is still poorly understood.
Dario Dattilo, Gaia Di Timoteo, A. Setti, Andrea Giuliani, G. Peruzzi, Manuel Beltran Nebot, Alvaro Centrón-Broco, D. Mariani, C. Mozzetta, I. Bozzoni   +9 more
semanticscholar   +1 more source

Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium

Journal of Clinical Oncology, 2021
PURPOSE Rhabdomyosarcoma is the most common soft tissue sarcoma of childhood. Despite aggressive therapy, the 5-year survival rate for patients with metastatic or recurrent disease remains poor, and beyond PAX-FOXO1 fusion status, no genomic markers are ...
J. Shern, J. Selfe, Elisa Izquierdo, R. Patidar, Hsien-Chao Chou, Young K. Song, M. Yohe, Sivasish Sindiri, Jun S. Wei, Xinyu Wen, E. Rudzinski, D. Barkauskas, Tammy Lo, David Hall, C. Linardic, Debbie Hughes, S. Jamal, M. Jenney, J. Chisholm, Rebecca M Brown, K. Jones, B. Hicks, P. Angelini, Sally L. George, L. Chesler, M. Hubank, A. Kelsey, S. Gatz, S. Skapek, D. Hawkins, J. Shipley, Javed Khan   +31 more
semanticscholar   +1 more source

Evolving classification of rhabdomyosarcoma

Histopathology, 2021
Rhabdomyosarcomas comprise the single largest category of soft tissue sarcomas in children and adolescents in the United States, occurring in 4.5 million people aged below 20 years.
Narasimhan P. Agaram
semanticscholar   +1 more source

Pediatric Rhabdomyosarcoma: Epidemiology and Genetic Susceptibility

Journal of Clinical Medicine, 2021
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children, yet little is known about its etiology. Studies that examine either environmental exposures or germline genetic predisposition in RMS have begun to identify factors that ...
Bailey A Martin-Giacalone, P. Weinstein, S. Plon, P. Lupo   +3 more
semanticscholar   +1 more source

Rhabdomyosarcoma of the uterus in an adult patient with osteopetrosis: a case report

Journal of Medical Case Reports, 2021
Background Uterine sarcoma accounts for 3–7% of uterine malignant neoplasms. It is more aggressive than epithelial neoplasms, and patients have a poor prognosis. Rhabdomyosarcoma is classified as a heterologous uterine sarcoma. It is the most common soft
Soheila Aminimoghaddam, Ali Rahbari, Roghayeh Pourali   +2 more
doaj   +1 more source

European guideline for imaging in paediatric and adolescent rhabdomyosarcoma — joint statement by the European Paediatric Soft Tissue Sarcoma Study Group, the Cooperative Weichteilsarkom Studiengruppe and the Oncology Task Force of the European Society of Paediatric Radiology

Pediatric Radiology, 2021
Appropriate imaging is essential in the treatment of children and adolescents with rhabdomyosarcoma. For adequate stratification and optimal individualised local treatment utilising surgery and radiotherapy, high-quality imaging is crucial.
R. van Ewijk, R. Schoot, M. Sparber-Sauer, S. T. ter Horst, N. Jehanno, L. Borgwardt, B. de Keizer, J. Merks, A. de Luca, K. McHugh, T. von Kalle, J. Schäfer, R. van Rijn, Amine Ana Pier Luigi Raquel Davila Christiane Chiara Gid Bouhamama Coma Di Paolo Fajardo Franzius Giraudo d, A. Bouhamama, A. Coma, P. D. Di Paolo, R. Fajardo, C. Franzius, C. Giraudo, Gideon M. de Jonge, D. Levine, D. Macvicar, H. Mandeville, S. Moholkar, C. Morosi, L. Müller, E. Pace, T. Rogers, Sheila Terwisscha van Scheltinga, N. Tolboom   +30 more
semanticscholar   +1 more source