Embryonal Rhabdomyosarcoma - A Mimicker of Squamosal Otitis Media [PDF]
Introduction: Rhabdomyosarcoma is the most frequently occurring intrusive soft tissue sarcoma in the pediatric age group. Orbit is the most common location for a pediatric rhabdomyosarcoma, but it can occur in the oral cavity, pharynx, face and neck in ...
Ajay Bhandarkar +3 more
doaj +1 more source
Rhabdomyosarcoma (RMS) merupakan tumor ganas pada jaringan lunak yang sering mengenai anak-anak. Lokasi primernya 25-30% pada orbita. Tumor ini merupakan tumor yang agresif, dengan kecenderung terjadi invasif lokal dan dapat terjadi rekurensi lokal ...
Rahman, Ardizal, Puteri, Elfi Risalma
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Embryonal rhabdomyosarcoma of the adult soft palate
Embryonal rhabdomyosarcoma is the most common soft tissue sarcoma in children. We report a rare case of embryonal rhabdomyosarcoma of the soft palate in a 32-year-old Caucasian female. Detailed histology of the tumor is described.
Samar Bhutoria, Ciaran ONeil
doaj +1 more source
Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein [PDF]
Tumors have evolved elaborate mechanisms for evading immune detection, such as production of immunoinhibitory cytokines and down-regulation of major histocompatibility complex (MHC) expression.
Hubank, M +21 more
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Immune targeting of autocrine IGF2 hampers rhabdomyosarcoma growth and metastasis
Background Insulin-like Growth Factor Receptor-1 (IGF1R) system sustains the genesis of rhabdomyosarcoma through IGF2 autocrine overexpression. While several IGF1R-targeted strategies have been investigated to interphere with rhabdomyosarcoma growth, no ...
Carla De Giovanni +7 more
doaj +1 more source
A RARE CASE REPORT OF PARATESTICULAR RHABDOMYOSARCOMA IN AN ADULT PATIENT
Rhabdomyosarcoma is a malignancy of mesenchymal tissue origin typically occurring in childhood and adolescence, with an incidence rate of of 4.3 patients per million population per anum. Primary rhabdomyosarcoma of para-testicular origin is an infrequent
Mussadique Ali +5 more
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Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma [PDF]
Gene expression profiling has revealed that the gene coding for cannabinoid receptor 1 (CB1) is highly up-regulated in rhabdomyosarcoma biopsies bearing the typical chromosomal translocations PAX3/FKHR or PAX7/FKHR.
Salazar, M +14 more
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Repositioning Bazedoxifene as a novel IL-6/GP130 signaling antagonist for human rhabdomyosarcoma therapy. [PDF]
Interleukins-6 (IL-6)/GP130 signaling pathway represents a promising target for cancer therapy due to its critical role in survival and progression of multiple types of cancer.
Hui Xiao +9 more
doaj +1 more source
Breast metastasis in an adult woman with alveolar rhabdomyosarcoma of the ethmoid sinus
A new breast mass was identified in an adult woman undergoing treatment for a known ethmoid sinus alveolar rhabdomyosarcoma. Histopathological evaluation revealed alveolar rhabdomyosarcoma metastatic to the breast.
Sean D. Raj, MD +4 more
doaj +1 more source
Orbital rhabdomyosarcoma in an adult [PDF]
Introduction: Rhabdomyosarcoma is the most common primary orbital malignant tumor in children. Orbital lesions represent about 10 % of all the cases of rhabdomyosarcoma. Rhabdomyosarcoma is a rare cause of proptosis in adults. Objective: To report a case
A Sinha +5 more
core +1 more source

