Journal of Pediatric Surgery Case Reports, 2018 Pediatric malignancies are thought to be risk factors of second malignant neoplasms. However, lung cancer associated with rhabdomyosarcoma is extremely rare.
Tatsuo Furuya +8 more
doaj +1 more source
Phase 1 study of sirolimus in combination with oral cyclophosphamide and topotecan in children and young adults with relapsed and refractory solid tumors. [PDF]
, 2016 PurposeTo determine the maximum tolerated dose (MTD), toxicities, and pharmacodynamics effects of sirolimus combined with oral metronomic topotecan and cyclophosphamide in a pediatric population.Materials and methodsPatients who were 1 to 30 years of age
Allen, Shelly +9 more
core +1 more source
Rhabdomyosarcoma of the kidney
Journal of Pediatric Surgery Case Reports, 2018 Rhabdomyosarcoma is considered the most common soft tissue sarcoma arising in patients younger than 15 years old, accounting for 5%–10% of childhood solid tumors. Sarcoma of the kidney represents 1% of all primary renal malignancies.
Alaa Samkari, Haneen Al-Maghrabi
doaj +1 more source
Cell death pathways as therapeutic targets in rhabdomyosarcoma [PDF]
, 2012 Resistance of rhabdomyosarcoma to current therapies remains one of the key issues in pediatric oncology. Since the success of most cytotoxic therapies in the treatment of cancer, for example, chemotherapy, depends on intact signaling pathways that ...
Fulda, Simone
core +1 more source
Dedifferentiation of an intracranial leptomeningeal solitary fibrous tumor to a rhabdomyosarcoma
Human Pathology Reports, 2022 Solitary fibrous tumors are fibroblastic mesenchymal neoplasms that also include what was previously known as hemangiopericytoma. Dedifferentiation of solitary fibrous tumors is rare and usually manifests as a high-grade sarcoma.
Roa Alqabbani +3 more
doaj +1 more source
BMN673 sensitizes rhabdomyosarcoma tumors to irradiation in vivo [PDF]
, 2020 Bone and soft tissue sarcomas are mesenchymal tumors that occur rarely in adults, representing only 1% of total malignancies, but comprise up to 13% of malignant tumors in children.1 Rhabdomyosarcoma, a soft tissue sarcoma that commonly affects children,
Jacob, Connor
core
Crizotinib-induced antitumour activity in human alveolar rhabdomyosarcoma cells is not solely dependent on ALK and MET inhibition [PDF]
, 2015 BACKGROUND: Rhabdomyosarcoma (RMS) is the most commonly diagnosed malignant soft tissue tumour in children and adolescents. Aberrant expression of Anaplastic Lymphoma Kinase (ALK) and MET gene has been implicated in the malignant progression of RMS ...
CAMERO, SIMONA +11 more
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Breast metastasis from multiple primary rhabdomyosarcoma in upper extremity
Clinics and Practice, 2012 We report a 16-year-old girl with a multiple primary rhabdomyosarcoma of right upper extremity who developed contralateral breast metastasis in her clinical course.
Ramesh Omranipour, Mohamad Reza Hadi
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ESF-EMBO symposium "molecular biology and innovative therapies in sarcomas of childhood and adolescence" Sept 29–Oct 4, Polonia Castle Pultusk, Poland [PDF]
, 2013 Rhabdomyosarcoma (RMS) and Ewing sarcoma (ES) are among the most common pediatric sarcomas (Arndt et al., 2012). Despite sarcomas representing a highly heterogeneous group of tumors, ES and alveolar RMS (ARMS) typically share one common genetic ...
Fulda, Simone +3 more
core +2 more sources
Insurance impacts survival for children, adolescents, and young adults with bone and soft tissue sarcomas. [PDF]
, 2020 BackgroundWhile racial/ethnic survival disparities have been described in pediatric oncology, the impact of income has not been extensively explored. We analyzed how public insurance influences 5-year overall survival (OS) in young patients with sarcomas.
Goldsby, Robert E +5 more
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