Results 71 to 80 of about 99,358 (330)
Cancer Research, 2020 This study elucidates the signaling pathways that regulate the oncogenic protein YAP1 and identifies a combination therapy to target these pathways in the childhood tumor rhabdomyosarcoma. Rhabdomyosarcoma is the most common childhood soft-tissue sarcoma,
Katherine K. Slemmons +5 more
semanticscholar +1 more source
From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies
Advanced Science, EarlyView.This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen +7 more
wiley +1 more source
Rhabdomyosarcoma of the nasal cavity: a case report
European Journal of Case Reports in Internal Medicine, 2023 Introduction: Rhabdomyosarcoma is a high-grade malignant neoplasm with skeletal muscle differentiation; a common soft tissue sarcoma in children but considered one of the rarest in adults.
Meiying Huang, Bifan Deng
doaj +1 more source
Cancer, 2020 New immunotherapeutic approaches are urgently needed for metastatic rhabdomyosarcoma, which is associated with poor survival and unsatisfactory treatment outcomes.
W. Xiao +10 more
semanticscholar +1 more source
Sinonasal Sarcomas Management: An International Consensus Statement
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Introduction Sinonasal sarcomas are exceedingly rare entities, constituting less than 7% of head and neck sarcomas. Their complex histology needs specialized treatment, which is often based on multimodal approaches including surgery, radiation therapy, and/or chemotherapy.
Alessandro Vinciguerra +51 more
wiley +1 more source
Paediatric Para-Meningeal Alveolar Rhabdomyosarcoma in the Nasal Cavity
Bengal Journal of Otolaryngology and Head Neck SurgeryIntroduction Rhabdomyosarcoma is the second most common malignant soft tissue tumor, which is of skeletal muscle in origin. Alveolar subtype of rhabdomyosarcoma is commonly seen in 10-25 years of age. We present a rare case of alveolar rhabdomyosarcoma
Cindya Vidyadharan +2 more
doaj +1 more source
Cancer, 2019 The objective of this study was to evaluate local control for patients with intermediate‐risk rhabdomyosarcoma (RMS) treated on Children's Oncology Group (COG) protocol ARST0531.
D. Casey +11 more
semanticscholar +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Background/aim This study evaluated cesarean section scar endometriosis (CSSE) characteristics and compared adipose‐ and muscle‐layer CSSEs. Materials and methods We analyzed 53 patients who underwent CSSE surgery between 2019‐2024, with 38 (71.7%) having adipose‐layer and 15 (28.3%) having muscle‐layer CSSE.
Emre Erdem Taş +3 more
wiley +1 more source
MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma
Science Translational Medicine, 2018 MEK inhibition decreases cell viability and induces differentiation in RAS-driven rhabdomyosarcoma via an epigenetic mechanism. Muscling in on RAS Rhabdomyosarcomas occur when skeletal muscle precursors fail to differentiate.
M. Yohe +23 more
semanticscholar +1 more source
Liposarcoma Arising From Mature Teratoma Following Testicular Tumor Surgery: A Case Report
IJU Case Reports, EarlyView.ABSTRACT Introduction Testicular germ cell tumors (GCTs) are rare cancers. Mature teratomas may rarely undergo somatic malignant transformation (SMT) and may exhibit histological features resembling those of sarcomas. Case A 22‐year‐old male presented to our hospital with a complaint of a left scrotal mass.
Mai Yamazaki +8 more
wiley +1 more source