Results 71 to 80 of about 50,529 (255)

Asymptomatic Cardiotoxicity After High‐Dose Anthracycline Treatment in Sarcoma Patients Assessed by Biomarkers and Echocardiography

International Journal of Cancer, EarlyView.
ABSTRACT Treatment of sarcoma includes high‐dose anthracyclines, which can cause cardiotoxicity. This study assesses the correlation of cardiac biomarkers and echocardiographic parameters on asymptomatic cardiotoxicity in sarcoma patients treated with anthracyclines.
Elissa A. S. Polomski, Frank M. Speetjens, J. Wouter Jukema, Julius C. Heemelaar, Michiel A. J. van de Sande, Hans Gelderblom, M. Louisa Antoni   +6 more
wiley   +1 more source

Inhibition of lipid metabolism exerts antitumor effects on rhabdomyosarcoma

Cancer Medicine, 2021
Rhabdomyosarcoma exhibits tumor‐specific energy metabolic changes that include the Warburg effect. Since targeting cancer metabolism is a promising therapeutic approach, we examined the antitumor effects of suppressing lipid metabolism in ...
Satoshi Miyagaki, Ken Kikuchi, Jun Mori, Gary D. Lopaschuk, Tomoko Iehara, Hajime Hosoi   +5 more
doaj   +1 more source

Diagnosis by Resolution: Ultrasound Follow‐Up of Neonatal Polypoid Cystitis Mimicking Botryoid Rhabdomyosarcoma

Journal of Clinical Ultrasound, EarlyView.
In neonatal bladder masses, benign inflammatory conditions like polypoid cystitis can mimic malignancy on ultrasound. In stable neonates with evidence of infection, short‐interval ultrasound follow‐up after antibiotic therapy allows “diagnosis by resolution.” This conservative approach safely avoids unnecessary invasive procedures while maintaining ...
Davide Meneghesso, Mattia Pasquinucci, Martina Bruniera, Filippo Carletti, Alessandro Morlacco   +4 more
wiley   +1 more source

Congenital Rhabdomyosarcoma Presenting as a Neck Mass at Birth

Case Reports in Pediatrics, 2018
Rhabdomyosarcoma is a malignant tumor of the soft tissues which preferentially affects the pediatric population. Neonatal rhabdomyosarcoma is rare, and much of the published literature concerning this entity consists of isolated case reports and small ...
Leah E. Waldman, Alex K. Williamson, John B. Amodio, Lee Collins   +3 more
doaj   +1 more source

Detection of chromosomal regions showing differential gene expression in human skeletal muscle and in alveolar rhabdomyosarcoma

BMC Bioinformatics, 2004
Background Rhabdomyosarcoma is a relatively common tumour of the soft tissue, probably due to regulatory disruption of growth and differentiation of skeletal muscle stem cells.
Bortoluzzi Stefania, Bisognin Andrea, Danieli Gian   +2 more
doaj   +1 more source

Current Evidence for Circulating Tumor DNA in Sarcoma: Challenges and Opportunities for Clinical Application

Journal of Surgical Oncology, EarlyView.
ABSTRACT Sarcomas represent a diverse group of mesenchymal tumors with high rates of recurrence after resection. While recent technical advances have enabled the detection of rare circulating tumor DNA (ctDNA) in other malignancies, the complexity and heterogeneity of sarcoma genomics have historically limited ctDNA in these cancers.
Kristin E. Goodsell, Jason A. Carter, Hannah R. Abrams, Harveshp Mogal, Elizabeth T. Loggers, Jeremy Sharib   +5 more
wiley   +1 more source

A subset of high-grade sarcomas with myogenic differentiation are associated with recurrent FGFR fusions. [PDF]

J Pathol Clin Res
Abstract Recurrent fusions involving FGFR1‐4 genes have been previously described in rare subsets of mostly benign chondroid and mesenchymal neoplasms involving bone and soft tissue. However, a more comprehensive analysis of sarcomas associated with FGFR fusions, including their incidence and histotypes, has not been performed.
Yeung MC, Saoud C, Chiang S, Hameed M, Antonescu CR.   +4 more
europepmc   +2 more sources

Optimization of the Cell‐Based Assay Methodology to Study Degradation of Acetylcholine Receptors (Antigenic Modulation) by Antibodies From Myasthenia Gravis Patients

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Degradation of cell‐surface acetylcholine receptors (AChRs) by antigenic modulation is a key pathogenic mechanism of myasthenia gravis (MG) autoantibodies, yet standard assays primarily detect antibody binding rather than functional effects.
Peng Du, Marina Mané‐Damas, Fien M. Verhamme, Mahan Moshir, Peter Ulrichts, Barbie Machiels, Mario Losen, Pilar Martinez‐Martinez   +7 more
wiley   +1 more source

Cyclin D1 as a Useful Marker for the Differentiation of Ewing’s Sarcoma from Rhabdomyosarcoma

Middle East Journal of Cancer, 2020
Background: The main oncogenic action of CD99 and cyclin D1 biomarkers is referred to any mutation, amplification, and overexpression in cyclin D1 coding gene, altering cell cycle progression as the main mechanism observed in a variety of tumors.
Tina Shooshtarizadeh, Ladan Fereidooni, Dorna Motevalli   +2 more
doaj   +1 more source

Applications and prospects of artificial intelligence and digital medicine in pediatric nasal skull base tumors

Pediatric Investigation, EarlyView.
Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu, Jing Wei, Chen Liu, Pengpeng Wang, Wentong Ge, Yang Han   +5 more
wiley   +1 more source