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Evolution of Genome Size and Complexity in the Rhabdoviridae
PLoS Pathogens, 2015 (Uploaded by Plazi for the Bat Literature Project) RNA viruses exhibit substantial structural, ecological and genomic diversity. However, genome size in RNA viruses is likely limited by a high mutation rate, resulting in the evolution of various mechanisms to increase complexity while minimising genome expansion.
S Istin, Cadhla Firth, Steven G Widen
exaly +7 more sources
ICTV Virus Taxonomy Profile: Rhabdoviridae [PDF]
Journal of General Virology, 2018 This is the final version of the article. Available from the publisher via the DOI in this record.The family Rhabdoviridae comprises viruses with negative-sense (-) single-stranded RNA genomes of 10.8-16.1 kb.
Peter J Walker +2 more
exaly +7 more sources
Resistance to Rhabdoviridae Infection and Subversion of Antiviral Responses [PDF]
Viruses, 2015 Interferon (IFN) treatment induces the expression of hundreds of IFN-stimulated genes (ISGs). However, only a selection of their products have been demonstrated to be responsible for the inhibition of rhabdovirus replication in cultured cells; and only a few have been shown to play a role in mediating the antiviral response in vivo using gene knockout ...
Sébastien Nisole
exaly +7 more sources
Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae). [PDF]
BMC Genetics, 2009 BACKGROUND: ADARs are RNA editing enzymes that target double stranded RNA and convert adenosine to inosine, which is read by translation machinery as if it were guanosine.
Carpenter, Jennifer A +4 more
core +10 more sources
Interferon Response and Viral Evasion by Members of the Family Rhabdoviridae [PDF]
Viruses, 2009 Like many animal viruses, those of the Rhabdoviridae family, are able to antagonize the type I interferon response and cause disease in mammalian hosts. Though these negative-stranded RNA viruses are very simple and code for as few as five proteins, they have been seen to completely abrogate the type I interferon response early in infection.
Matthias J Schnell
exaly +5 more sources
The Transcriptional Response of Drosophila melanogaster to Infection with the Sigma Virus (Rhabdoviridae) [PDF]
PLoS ONE, 2009 Bacterial and fungal infections induce a potent immune response in Drosophila melanogaster, but it is unclear whether viral infections induce an antiviral immune response. Using microarrays, we examined the changes in gene expression in Drosophila that occur in response to infection with the sigma virus, a negative-stranded RNA virus (Rhabdoviridae ...
John F Baines, Francis M Jiggins
exaly +8 more sources
Genomics and structure/function studies of Rhabdoviridae proteins involved in replication and transcription [PDF]
Antiviral Research, 2010 Some mammalian rhabdoviruses may infect humans, and also infect invertebrates, dogs, and bats, which may act as vectors transmitting viruses among different host species. The VIZIER programme, an EU-funded FP6 program, has characterized viruses that belong to the Vesiculovirus, Ephemerovirus and Lyssavirus genera of the Rhabdoviridae family to perform ...
Johan Neyts, Alexander E Gorbalenya
exaly +11 more sources
Review of Rabies Preventions and Control [PDF]
, 2017 Rabies is an acute viral infection of the central nervous system, caused by a lyssavirus in the family Rhabdoviridae. It is zoonotic viral disease that can affect all mammals, including humans, cats, dogs, and wildlife and farm animals.
Abdela, N. (Nejash) +1 more
core +2 more sources
Identification of rhabdoviral sequences in oropharyngeal swabs from German and Danish bats [PDF]
, 2014 BACKGROUND: In the frame of active lyssavirus surveillance in bats, oropharyngeal swabs from German (N = 2297) and Danish (N = 134) insectivorous bats were investigated using a newly developed generic pan-lyssavirus real-time reverse transcriptase PCR ...
Balkema-Buschmann, Anne +8 more
core +1 more source
Antigenic and genetic characterization of a divergent African virus, Ikoma lyssavirus [PDF]
, 2014 In 2009, a novel lyssavirus (subsequently named Ikoma lyssavirus, IKOV) was detected in the brain of an African civet (Civettictis civetta) with clinical rabies in the Serengeti National Park of Tanzania.
Alejandro Nunez +21 more
core +2 more sources