Results 81 to 90 of about 10,000 (240)

Lyophilisation of influenza, rabies and Marburg lentiviral pseudotype viruses for the development and distribution of a neutralisation-assay based diagnostic kit [PDF]

, 2014
Pseudotype viruses (PVs) are chimeric, replication-deficient virions that mimic wild-type virus entry mechanisms and can be safely employed in neutralisation assays, bypassing the need for high biosafety requirements and performing comparably to ...
Assar, Berge, Brauburger, Capecchi, Cliquet, Cox, Croyle, Demaison, Desvaux, Edward Wright, Fellowes, Gao, Higashikawa, Jackson, Kaku, Kishishita, Loi, Lowen, Mather, Molesti, Nigel J. Temperton, Noti, Papenburg, Pear, Scott, Scott, Shin, Simon D. Scott, Stoker, Stuart T. Mather, Temperton, Temperton, Terregino, To, Tong, Tyrrell, Wei, WHO, WHO, Wilschut, Wright, Wright, Wright, Yuen, Zufferey   +44 more
core   +3 more sources

The RNA interference response to alphanodavirus replication in Phlebotomus papatasi sand fly cells

Insect Molecular Biology, Volume 33, Issue 6, Page 687-696, December 2024.
Both the siRNA and piRNA pathways are transcriptionally active in Phlebotomus papatasi PP9ad cells. Assembly of small RNA sequencing identifies an adventitious nodavirus (American nodavirus [ANV]) in PP9ad cells. ANV is actively replicating in PP9ad cells and is targeted by the exo‐siRNA pathway but not the piRNA pathway.
Akira J. T. Alexander, Rhys H. Parry, Maxime Ratinier, Frédérick Arnaud, Alain Kohl   +4 more
wiley   +1 more source

Human, Nonhuman Primate, and Bat Cells Are Broadly Susceptible to Tibrovirus Particle Cell Entry

Frontiers in Microbiology, 2019
In 2012, the genome of a novel rhabdovirus, Bas-Congo virus (BASV), was discovered in the acute-phase serum of a Congolese patient with presumed viral hemorrhagic fever.
Yíngyún Caì, Shuǐqìng Yú, Rohit K. Jangra, Elena N. Postnikova, Jiro Wada, Robert B. Tesh, Sean P. J. Whelan, Michael Lauck, Michael R. Wiley, Courtney L. Finch, Sheli R. Radoshitzky, David H. O’Connor, Gustavo Palacios, Kartik Chandran, Charles Y. Chiu, Jens H. Kuhn   +15 more
doaj   +1 more source

Viral delivery of dsRNA for control of insect agricultural pests and vectors of human disease : prospects and challenges [PDF]

, 2017
RNAi is applied as a new and safe method for pest control in agriculture but efficiency and specificity of delivery of dsRNA trigger remains a critical issue. Various agents have been proposed to augment dsRNA delivery, such as engineered micro-organisms
Kolliopoulou, Anna, Smagghe, Guy, Swevers, Luc, Taning, Nji Tizi Clauvis   +3 more
core   +2 more sources

Vesicular Stomatitis Virus as a Platform for Protease Activity Measurements

Current Protocols, Volume 4, Issue 11, November 2024.
Abstract Protease inhibitors are among the most powerful antiviral drugs. They have been used successfully against viruses, such as the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
Stefanie Rauch, Francesco Costacurta, Dorothee von Laer, Emmanuel Heilmann   +3 more
wiley   +1 more source

Adeno-associated virus and lentivirus vectors: a refined toolkit for the central nervous system. [PDF]

, 2016
The last two decades have witnessed the increasing instrumentalization of viruses, which have progressively evolved into highly potent gene transfer vehicles for a wide spectrum of applications.
Blessing, D., Déglon, N.
core   +1 more source

Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39

British Journal of Pharmacology, Volume 181, Issue 22, Page 4450-4490, November 2024.
Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier, Viktoria M. S. Kjær, Stephen Griffin, Birthe B. Kragelund, Mette M. Rosenkilde   +4 more
wiley   +1 more source

Candidates in Astroviruses, Seadornaviruses, Cytorhabdoviruses and Coronaviruses for +1 frame overlapping genes accessed by leaky scanning

Virology Journal, 2010
Background Overlapping genes are common in RNA viruses where they serve as a mechanism to optimize the coding potential of compact genomes. However, annotation of overlapping genes can be difficult using conventional gene-finding software.
Atkins John F, Firth Andrew E
doaj   +1 more source

“Heroic” medicine in neurology: A historical perspective

European Journal of Neurology, Volume 31, Issue 11, November 2024.
Abstract Background and purpose Repetitive bloodletting, promoting profuse diarrhoea and vomiting, the formation of artificial ulcers, and other aggressive treatment methods based on humoral theory and Brunonian medicine were used for patients with nervous system (NS) diseases until the end of the 19th century.
Eglė Sakalauskaitė‐Juodeikienė
wiley   +1 more source

Public Health Surveillance for Australian bat lyssavirus in Queensland, Australia, 2000–2001

Emerging Infectious Diseases, 2003
From February 1, 2000, to December 4, 2001, a total of 119 bats (85 Megachiroptera and 34 Microchiroptera) were tested for Australian bat lyssavirus (ABLV) infection. Eight Megachiroptera were positive by immunofluorescence assay that used cross-reactive
David Warrilow, Bruce Harrower, Ina L. Smith, Hume E. Field, Roscoe Taylor, G. Craig Walker, Greg A. Smith   +6 more
doaj   +1 more source