Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39
Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier+4 more
wiley +1 more source
Protection against myxomatosis and rabbit viral hemorrhagic disease with recombinant myxoma viruses expressing rabbit hemorrhagic disease virus capsid protein [PDF]
Two myxoma virus-rabbit hemorrhagic disease virus (RHDV) recombinant viruses were constructed with the SG33 strain of myxoma virus to protect rabbits against myxomatosis and rabbit viral hemorrhagic disease.
Bertagnoli, Stéphane+9 more
core +2 more sources
Abstract Infectious diseases can cause considerable mortality in vertebrate populations, especially when a new pathogen emerges. Quantifying the impact of diseases on wild populations and dissecting the underlying mechanisms requires longitudinal individual monitoring combining demographic and epidemiologic data.
Jérôme Letty+7 more
wiley +1 more source
Molecular and Histopathological Studies on Currently Circulating RHDV in Rabbit Farms in Egypt
The current study aimed to identify rabbit hemorrhagic disease virus (RHDV) causing high mortality in rabbit farms from May 2018 to December 2020 as well as its genetic variation and histopatological picture in natural outbreaks. A total of 12 rabbit flocks from different localities of Alexandria governorate were investigated for RHDV depending on the
Disouky Mohamed Mourad+5 more
openaire +2 more sources
RNA-Dependent RNA Polymerases of Both Virulent and Benign Rabbit Caliciviruses Induce Striking Rearrangement of Golgi Membranes. [PDF]
The extremely pathogenic Rabbit haemorrhagic disease virus (RHDV) and the completely benign Rabbit calicivirus (RCV) are closely related members of the genus Lagovirus (family Caliciviridae).
Nadya Urakova+2 more
doaj +1 more source
Remote sensing for rangeland conservation monitoring: Impacts of livestock removal after 15 years
The ability to quantify management‐related impacts in land condition using freely available remote sensing data could support improved management by all stakeholders in these regions. The method leverages readily available satellite remote sensing data in a study design that is not dependent on large geospatial and climatic datasets that are not ...
Angus Retallack+4 more
wiley +1 more source
Rabbit Hemorrhagic Disease Virus Non-structural Protein 6 Induces Apoptosis in Rabbit Kidney Cells
Rabbit hemorrhagic disease (RHD) is a highly contagious disease caused by rabbit hemorrhagic disease virus (RHDV). Previous research has shown that RHDV induces apoptosis in numerous cell types, although the molecular mechanisms underlying the apoptosis ...
Mengmeng Chen+9 more
doaj +1 more source
Abstract Background Coxiella burnetii, the causative agent of Q fever, is a zoonotic multi‐host vector‐borne pathogen of major public health importance. Although the European Food Safety Authority has recently made the monitoring of this bacterium in wildlife a priority, the role of wild lagomorphs in the transmission and maintenance of C.
Sabrina Castro‐Scholten+9 more
wiley +1 more source
Genetic characterization of interleukins (IL-1α, IL-1β, IL-2, IL-4, IL-8, IL-10, IL-12A, IL-12B, IL-15 and IL-18) with relevant biological roles in lagomorphs [PDF]
Disponível em: www.ncbi.nlm.nih.gov/pmc/articles/pmid/26395994/ILs, as essential innate immune modulators, are involved in an array of biological processes.
Abrantes, J.+5 more
core +1 more source
Using bioindicators to inform effective predator management for threatened species protection
Abstract In Australia, most threatened species translocations conducted into areas where feral predators are present fail to establish viable, self‐sustaining populations despite intensive predator control. These translocations are occurring amidst a lack of understanding regarding the conditions required for native species to survive, including ...
C. A. Adams+4 more
wiley +1 more source