Results 161 to 170 of about 76,583 (247)

Efficacy and Safety of Intralymphatic Immunotherapy With Grass Allergoid and Microcrystalline Tyrosine: A Double‐Blind Randomised Placebo‐Controlled Trial

Allergy, EarlyView.
This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of
Lara Šošić, Stephan C. Flory, Claudia C. V. Lang, Emma C. Widmer, Alexandra Chabot, Johannes M. Schmid, Tobias Andermatt, David Melillo, Bjarke Hviid‐Vyff, Maibritt Mardahl, Peter Schmid‐Grendelmeier, Thomas M. Kündig, Hans Jürgen Hoffmann, Pål Johansen   +13 more
wiley   +1 more source

Einschreibungsordnung der Hochschule Bonn-Rhein-Sieg vom 04.08.2021 in der Fassung der Änderungsordnung der Hochschule Bonn-Rhein-Sieg vom 15.12.2022 [PDF]

, 2022
Hochschule Bonn-Rhein-Sieg
core   +1 more source

Berberine-Mediated BCRP Inhibition Enhances Systemic Exposure of Rhein: A Study to Unravel the Pharmacokinetic Basis of Synergy in Da-Huang-Xiao-Shi Decoction. [PDF]

Pharmaceuticals (Basel)
Xu Z, Li H, Xue H, Wang X, Wang T, Zhou Y, Gu J, Shi R.   +7 more
europepmc   +1 more source

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Einwohnerprognose Ludwigshafen am Rhein ...

EINWOHNERPROGNOSE LUDWIGSHAFEN AM RHEIN ... Einwohnerprognose Ludwigshafen am Rhein ...

core  

Male Mice Heterozygous for Protamine 1 and Protamine 2 Are Infertile, Displaying Sperm Damage and Retention of Protamine 2 Precursors, Transition Proteins, and Histones

Andrology, EarlyView.
ABSTRACT Background During spermiogenesis, protamines (PRMs) replace histones to hypercondense and protect sperm DNA. Rodents and primates express two PRMs (PRM1 and PRM2). Alterations of species‐specific PRM ratios are associated with sub‐ or infertility in mice and humans.
Gina Esther Merges, Christoph Wiesejahn, Mar Domingo‐Lopez, Simon Schneider, Andjela Kovacevic, Lena Arévalo, Hubert Schorle   +6 more
wiley   +1 more source

Rhein Inhibits NLRP3 Activation and Alleviates Microglial Pyroptosis After Intracerebral Hemorrhage in Rats. [PDF]

Brain Behav
Aimaiti A, Li Q, Liu T, Chen C, Xie X, Chu J, Nuermaimaiti D, Hu Y.   +7 more
europepmc   +1 more source

Prevention and Management of Driveline Infections in Ventricular Assist Device Patients: The DESTINE 2.0 Staging Proposal and Expert Recommendations

Artificial Organs, EarlyView.
DESTINE 2.0 decision flowchart: stage‐based assessment and management of driveline exit‐site disorders. The flowchart provides a simplified decision‐support tool for the stage‐based evaluation and management of driveline exit‐site disorders in LVAD patients, intended as a practical complement to the staging pyramid (Figre 2) and the detailed staging ...
Alexander M. Bernhardt, Volker Lauenroth, Florian Mueller, Friedrich Kaufmann, Katharina Homann, Martina Socha, Thomas Schlöglhofer, the Driveline Expert STagINg and carE (DESTINE) study group   +7 more
wiley   +1 more source

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Acta Ophthalmologica, EarlyView.
Abstract Purpose To measure the progression of geographic atrophy (GA) in subjects with age‐related macular degeneration (AMD) in a natural history study. Methods We analysed fundus autofluorescence (FAF) images using a semiautomatic method (RegionFinder) to quantify the GA area in a monocentric study.
Philippe Valmaggia, Georg Ansari, Nadja Inglin, Nils Schärer, Hanna Zuche, Chrysoula Gabrani, Faady Yahya, Marco Cattaneo, Kristina Pfau, Andrea Giani, Marieh Esmaeelpour, Taffeta Chingning Yamaguchi, Christian Prünte, Hendrik P. N. Scholl, Nicolas Feltgen, Leopold Schmetterer, Maximilian Pfau, Peter M. Maloca   +17 more
wiley   +1 more source

Huashi Baidu formula may attenuate adriamycin-induced myocardial injury via modulating NRF2-ATF3-SRXN1 axis-mediated ferroptosis. [PDF]

Chin Herb Med
Li W, Li X, Huang C, Liu Y, Ma Z, Zhou Z, Guo Q, Xia C, Wang C, Zhong Y, Wang P, Xu H.   +11 more
europepmc   +1 more source