Results 141 to 150 of about 14,550 (256)

Copper-rhein nanozymes induce bacterial activation-exhaustion death for the treatment of bacterial pneumonia and infected wounds. [PDF]

J Nanobiotechnology
Cui Y, Niu Q, Li Z, Jiang G, Zhao D, Luo C, Wei J, Cao D, Fan K, Zheng Y.   +9 more
europepmc   +1 more source

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

Rhein ameliorates inflammation, gut dysbiosis, and renal injury in obesity-related glomerulopathy mice. [PDF]

Front Pharmacol
Xu M, Yu Y, Li L, Zhao K, Lai J, Wei L, Ge L.   +6 more
europepmc   +1 more source

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Acta Ophthalmologica, EarlyView.
Abstract Purpose To measure the progression of geographic atrophy (GA) in subjects with age‐related macular degeneration (AMD) in a natural history study. Methods We analysed fundus autofluorescence (FAF) images using a semiautomatic method (RegionFinder) to quantify the GA area in a monocentric study.
Philippe Valmaggia, Georg Ansari, Nadja Inglin, Nils Schärer, Hanna Zuche, Chrysoula Gabrani, Faady Yahya, Marco Cattaneo, Kristina Pfau, Andrea Giani, Marieh Esmaeelpour, Taffeta Chingning Yamaguchi, Christian Prünte, Hendrik P. N. Scholl, Nicolas Feltgen, Leopold Schmetterer, Maximilian Pfau, Peter M. Maloca   +17 more
wiley   +1 more source

Regulation of feeding and metabolism by fat mass and obesity-associated protein in zebrafish. [PDF]

Sci Rep
Karimzadeh K, Uju C, Zahmatkesh A, Unniappan S.   +3 more
europepmc   +1 more source

Learning Across the Divide: Understanding Knowledge Sharing Through Petrographic Analysis on Ceramics From the Rhine‐Meuse Delta During the Middle to Late Neolithic Transition (3400–2200 bce)

Archaeometry, EarlyView.
ABSTRACT Vlaardingen (VL) communities on the Dutch West coast (3400–2200 bce) are part of a unique, long‐term continuity in the European Neolithic. Despite large‐scale changes in European populations during the Neolithic, the genomic diversity and cultural practices of VL communities can be retraced to the Mesolithic.
Jisca de Bruin, Erik Kroon, Lasse van den Dikkenberg, Dennis Braekmans   +3 more
wiley   +1 more source

Antibacterial activity of bioactive anthraquinones isolated from Cassia tora L. against pathogenic intestinal microorganisms. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Balusamy SR, Lee S, Anandapadmanaban G, Samad A, Shikder MR, Veeramani C, Alsaif MA, Al-Numair KS, Singh P, Perumalsamy H.   +9 more
europepmc   +1 more source

Late Iron Age and Early Roman Brooches From the Lower Rhine Area: Provenance of the Metal Supply Traced Through Lead Isotopes

Archaeometry, EarlyView.
ABSTRACT Geochemical analysis of five brooch types from the Lower Rhine area dated to the last century bc and first century ad is used to constrain resource use, exchange and mobility. Lead isotope ratios demonstrate an Iberian provenance for copper in bronze Late Iron Age brooches.
A. A. T. Ruiter, B. J. H. van Os, J. B. V. Hermsen, G. R. Davies, S. W. Merkel   +4 more
wiley   +1 more source

Separation and Characterization of Self-Assembled Nanoparticles from <i>Rheum palmatum</i> L.-<i>Salvia miltiorrhiza</i> Bunge Extract and Their Renoprotective Effects in Acute Kidney Injury. [PDF]

Antioxidants (Basel)
Yang J, Li C, Tang H, Xia X, Chen Y, Zhu M, Ye G, Shi F, Zhang W, Lv C, Li L, Wang X, Li Y, Zhao L.   +13 more
europepmc   +1 more source

Reduced colony‐stimulating factor 1 receptor expression in myeloid cells has limited impact on chronic lymphocytic leukaemia progression

British Journal of Haematology, EarlyView.
Summary Targeting the colony‐stimulating factor 1 receptor (CSF1R) to remove tumour‐associated macrophages is being explored as cancer therapy. This strategy may be relevant for chronic lymphocytic leukaemia (CLL), which strongly depends on support from myeloid cells.
Natascha Rosen, Guillermo Rodriguez‐Real, Alexander F. vom Stein, Luca D. Schreurs, Trong‐Hieu Nguyen, Viktoria Kohlhas, Thanh‐Tung Truong, Maximilian Koch, Sebastian Reinartz, Sumiya Iqbal, Shaista Ilyas, Sanjay Mathur, Nina Reinart, Phuong‐Hien Nguyen, Michael Hallek   +14 more
wiley   +1 more source