Results 61 to 70 of about 14,550 (256)

Rhein Reduces Fat Weight in db/db Mouse and Prevents Diet-Induced Obesity in C57Bl/6 Mouse through the Inhibition of PPARγ Signaling

open access: yesPPAR Research, 2012
Rheum palmatum has been used most frequently in the weight-reducing formulae in traditional Chinese medicine. However, the components of Rheum palmatum that play the antiobesity role are still uncertain.
Yu Zhang   +7 more
doaj   +1 more source

How Corporations Operationalize Climate‐Related Risks and Opportunities: Evidence From Qualitative Expert Interviews

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Climate‐related risks and opportunities have become a central concern for companies as climate change increasingly affects business models, value chains, and long‐term competitiveness. However, limited evidence exists about how corporations confront the attendant practical and strategic challenges of climate‐related risk and opportunity ...
Sebastian Rhein   +3 more
wiley   +1 more source

A novel phenolic propanediamine moiety-based lung-targeting therapy for asthma

open access: yesDrug Delivery, 2018
Asthma is one of the most prevalent chronic inflammatory diseases of lung. Current asthma therapy using inhaled corticosteroid often results in undesired treatment outcome due to poor compliance and drugs’ lack of tissue specificity. N,N,N’-trimethyl-N’-(
Jianbo Li   +4 more
doaj   +1 more source

From Circular Economy Disclosure to Circular Transformation: A Case Study From Food‐Producing Companies

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Changing the use of resources and the treatment of waste is an important driver towards sustainable development. While this includes transformation of production processes, it also requires the transition of complete business models towards more circularity.
Patricia Ruffing‐Straube   +2 more
wiley   +1 more source

Interplay of Bridge Topology and Conformation in Phenylene‐Bridged Trityl Diradicals

open access: yesChemistry – A European Journal, EarlyView.
We present a meta‐phenylene‐bridged trityl diradical that exhibits an unexpectedly weak antiferromagnetic exchange coupling J with a strong environment‐dependent magnitude. Combined VSM, EPR, DFT, and MD studies reveal that structural flexibility modulates σ‐, π‐, and through‐space exchange contributions, highlighting the crucial role of geometry in ...
Kevin Lars Kopp   +4 more
wiley   +1 more source

Rhein attenuates inflammation through inhibition of NF-κB and NALP3 inflammasome in vivo and in vitro

open access: yesDrug Design, Development and Therapy, 2017
Hui Ge,1,* Hao Tang,2,* Yanbing Liang,2 Jingguo Wu,2 Qing Yang,2 Lijin Zeng,2 Zhongfu Ma2 1Department of Health Care Clinic, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; 2Department of General Internal Medicine, the First ...
Ge H   +6 more
doaj  

Rhein promotes skin wound healing by activating the PI3K/AKT signaling pathway

open access: yesOpen Medicine
Rhein is a natural anthraquinone substance extracted from Rheum palmatum L. This study aimed to evaluate Rhein’s protective effects against skin wound by in vivo and in vitro models and investigate whether its protective mechanism regulated the PI3K/AKT ...
Yang Dong   +5 more
doaj   +1 more source

Defossilisation of the Energy Supply of a Chemical Site by Integration of a Carnot Battery

open access: yesChemie Ingenieur Technik, EarlyView.
This study presents the results of a techno‐economic analysis of CO2‐free energy supply concepts for electricity and heat for the defossilisation of a chemical park in Germany for the model years 2030 and 2045. The focus is on the integration of a Carnot battery with thermal energy storage, which enables the flexible use of green fuels and renewable ...
Martin Bolten   +6 more
wiley   +1 more source

Carbon2Chem—Innovative Research for the Energy Transition

open access: yesChemie Ingenieur Technik, EarlyView.
The Carbon2Chem project has been working on solutions for the energy transition since 2016. Despite changes in its framework conditions, the project remains on course. The project structure and the collaboration between the project partners are essential for the project's success.
Torsten Müller
wiley   +1 more source

Fluorescent Rhein-Loaded Liposomes for In Vivo Biodistribution Study

open access: yesPharmaceutics
Objectives: This work aimed to develop and investigate liposomes incorporating Rhein (Lip-Rh) into the liposomal membrane to enhance the compound’s water solubility and oral bioavailability.
Silviu Iulian Filipiuc   +8 more
doaj   +1 more source

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