Results 121 to 130 of about 174,225 (258)

Nonhuman Primate Model of Oculocutaneous Albinism with TYR and OCA2 Mutations

Research, 2020
Human visual acuity is anatomically determined by the retinal fovea. The ontogenetic development of the fovea can be seriously hindered by oculocutaneous albinism (OCA), which is characterized by a disorder of melanin synthesis.
Kun-Chao Wu, Ji-Neng Lv, Hui Yang, Feng-Mei Yang, Rui Lin, Qiang Lin, Ren-Juan Shen, Jun-Bin Wang, Wen-Hua Duan, Min Hu, Jun Zhang, Zhan-Long He, Zi-Bing Jin   +12 more
doaj   +1 more source

The Company We Keep: Effects of Different Social Environments on Male Guinea Pig Behaviour and Hormones Over the Course of the Ontogeny

Ethology, EarlyView.
To examine how their behaviour and hormones change over different life phases, male guinea pigs experienced two different social environments from juvenility to adulthood. Only one environment contained social stimulation by unfamiliar conspecifics. Although no differences in testosterone and cortisol concentrations were found, it was interesting that ...
Maximilian Baldy, Sylvia Kaiser
wiley   +1 more source

Characterisation of mouse monoclonal antibodies against rhesus macaque killer immunoglobulin-like receptors KIR3D [PDF]

, 2012
Killer immunoglobulin-like receptors (KIRs) represent a highly polymorphic and diverse gene family in rhesus macaques. Analyses of the respective gene products have been hampered until now due to non-availability of specific monoclonal antibodies and ...
Sandra Weil, Groth, Ariane, Ariane Groth, Weil, Sandra, Meike Hermes, Joachim Koch, Hermes, Meike, Walter, Lutz, Dressel, Ralf, Koch, Joachim, Ralf Dressel, Lutz Walter   +11 more
core   +1 more source

MHC and KIR Polymorphisms in Rhesus Macaque SIV Infection

Frontiers in Immunology, 2015
Natural killer lymphocytes are essentially involved as the first line of defense against agents such as viruses and malignant cells. The activity of these cells is regulated via interaction of specific and diverse killer cell immunoglobulin-like ...
L. Walter, A. Ansari
semanticscholar   +1 more source

Hepatitis C Virus Infects Rhesus Macaque Hepatocytes and Simianized Mice

Hepatology, 2015
At least 170 million people are chronically infected with hepatitis C virus (HCV). Owing to the narrow host range of HCV and restricted use of chimpanzees, there is currently no suitable animal model for HCV pathogenesis studies or the development of a ...
Margaret A. Scull, Chao Shi, Y. D. de Jong, G. Gerold, Moritz Ries, M. von Schaewen, B. M. Donovan, Rachael N. Labitt, J. Horwitz, Jenna M. Gaska, G. Hrebikova, Jing W. Xiao, Brenna R. Flatley, Canny Fung, L. Chiriboga, Christopher M. Walker, D. Evans, Charles M. Rice, A. Ploss   +18 more
semanticscholar   +1 more source

Albinism in a juvenile rhesus macaque Macaca mulatta (Zimmermann 1780) from the Brahmaputra Valley of Assam, India (Primates: Cercopithecidae)

Natural History Sciences
Color aberrations are rare phenomena in wild mammals and are often associated with genetic disruptions affecting melanin production or deposition. The rhesus macaque Macaca mulatta, one of the most widespread primate species in India, has only rarely ...
Neeraj Bora, Sanghamitra Buragohain, Deep Jyoti Borah, Chiranjib Bora, Sandip Choudhury, Jyotismita Das   +5 more
doaj   +1 more source

Neuroanatomy education through the years: Revisiting the teaching slides used by Sir Wilfrid Edward Le Gros Clark

Journal of Anatomy, EarlyView.
This paper examines the life and legacy of British anatomist Sir Wilfrid Le Gros Clark through his neuroanatomical teaching collection at the University of Oxford. The authors catalogued 103 specimens and analyzed selected slides—including cases of multiple sclerosis, amyotrophic lateral sclerosis, tabes dorsalis, syringomyelia, and the pineal gland's ...
Shiva A. Nischal, Kush M. Kale, Katherine Tourigny, Mohammed Abuelem, Gretchen Greene, Rachel Walsh, Zoltán Molnár   +6 more
wiley   +1 more source

Effective and stable gene transduction in rhesus macaque iPSCs capable of T-lineage differentiation utilizing the piggyBac system

Regenerative Therapy
Introduction: Genetically modified human induced pluripotent stem cell (iPSC)-based regenerative medicine has substantial potential in the treatment of refractory human diseases.
Masahiro Tanaka, Yoshihiro Iwamoto, Bo Wang, Eri Imai, Munehiro Yoshida, Shoichi Iriguchi, Shin Kaneko   +6 more
doaj   +1 more source

Periodontal considerations during orthodontic intrusion and extrusion in healthy and reduced periodontium

Periodontology 2000, EarlyView.
Abstract In patients with advanced periodontal disease, pathological tooth migration may occur, which may require subsequent orthodontic treatment for both aesthetic and functional purposes. When planning orthodontic treatment mechanics, intrusive or extrusive forces are frequently indicated.
Gregory S. Antonarakis, Alkisti Zekeridou, Stavros Kiliaridis, Catherine Giannopoulou   +3 more
wiley   +1 more source

Inactivated polio vaccination using a microneedle patch is immunogenic in the rhesus macaque

Vaccine, 2015
The phased replacement of oral polio vaccine (OPV) with inactivated polio vaccine (IPV) is expected to significantly complicate mass vaccination campaigns, which are an important component of the global polio eradication endgame strategy.
C. Edens, N. Dybdahl-Sissoko, W. Weldon, M. Oberste, M. Prausnitz   +4 more
semanticscholar   +1 more source