Results 111 to 120 of about 174,225 (258)

Auditory Rehabilitation in Rhesus Macaque Monkeys (Macaca mulatta) with Auditory Brainstem Implants

Chinese Medical Journal, 2015
Background: The auditory brainstem implants (ABIs) have been used to treat deafness for patients with neurofibromatosis Type 2 and nontumor patients. The lack of an appropriate animal model has limited the study of improving hearing rehabilitation by the
Zhen-Min Wang, Zhi-Jun Yang, Fu Zhao, Bo Wang, Xing-Chao Wang, Pei-Ran Qu, Pi-Nan Liu   +6 more
doaj   +1 more source

Seasonal Dynamics of Community and Function of Gut Microbiome in Taihangshan Macaque (Macaca mulatta tcheliensis): Inferred From Metagenomic Data

Integrative Zoology, EarlyView.
A total of 435 non‐redundant metagenome‐assembled genomes (MAGs) were obtained from fecal samples of Taihangshan macaque across all four seasons. The alpha diversity of the gut microbiome in spring and winter was significantly higher than in summer and autumn. Furthermore, marked differences were detected in functional pathways and carbohydrate enzymes
Yanyan Zhou, Qi Shao, Chunbo Liu, Jundong Tian, Xiaowen Guan, Xi Zhang, Jiqi Lu   +6 more
wiley   +1 more source

Biogeography of the Intestinal Mucosal and Lumenal Microbiome in the Rhesus Macaque

Cell Host and Microbe, 2015
Summary The gut microbiome is widely studied by fecal sampling, but the extent to which stool reflects the commensal composition at intestinal sites is poorly understood.
K. Yasuda, Keunyoung Oh, Boyu Ren, Timothy L. Tickle, E. Franzosa, L. Wachtman, Andrew D. Miller, S. Westmoreland, K. Mansfield, E. Vallender, G. Miller, J. Rowlett, D. Gevers, C. Huttenhower, X. Morgan   +14 more
semanticscholar   +1 more source

Respiratory disease in rhesus macaques inoculated with SARS-CoV-2

Nature, 2020
An outbreak of coronavirus disease 2019 (COVID-19), which is caused by a novel coronavirus (named SARS-CoV-2) and has a case fatality rate of approximately 2%, started in Wuhan (China) in December 20191,2.
V. Munster, F. Feldmann, Brandi N. Williamson, N. van Doremalen, L. Pérez-Pérez, Jonathan E. Schulz, Kimberly Meade-White, A. Okumura, Julie A. Callison, Beniah Brumbaugh, V. Avanzato, Rebecca Rosenke, P. Hanley, G. Saturday, D. Scott, E. Fischer, E. de Wit   +16 more
semanticscholar   +1 more source

Visual information processing, welfare, and cognition in the rhesus macaque [PDF]

, 2016
Visual information processing, welfare, and cognition in the rhesus macaque - Chapter one deals with motion and disparity in macaque monkeys' area MST and their functional independence.
Calapai, Antonino
core   +1 more source

Dystrophia Smolandiensis is characterized by a novel NQO1 variant and a distinct phenotype from COL17A1‐associated epithelial recurrent erosion dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer, Kristina Lagerstedt‐Robinson, Daniel Nilsson, Cilla Söderhäll, Björn Hammar, Erik Björck   +5 more
wiley   +1 more source

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

Nature, 2020
Effective therapies to treat coronavirus disease 2019 (COVID-19) are urgently needed. While many investigational, approved, and repurposed drugs have been suggested as potential treatments, preclinical data from animal models can guide the search for ...
Brandi N. Williamson, F. Feldmann, B. Schwarz, Kimberly Meade-White, D. Porter, Jonathan E. Schulz, N. van Doremalen, I. Leighton, C. Yinda, L. Pérez-Pérez, A. Okumura, J. Lovaglio, P. Hanley, G. Saturday, C. Bosio, S. Anzick, Kent D. Barbian, T. Cihlář, C. Martens, D. Scott, V. Munster, E. de Wit   +21 more
semanticscholar   +1 more source

Trace Element Patterns in Juvenile Wild Chimpanzee Dentitions

Archaeometry, EarlyView.
ABSTRACT Trace elements are used to infer mammalian early‐life diets, environmental toxins, dispersal patterns, stress histories, and weaning ages. Here, we employ laser ablation‐inductively coupled plasma‐mass spectrometry (LA‐ICP‐MS) to reveal elemental patterns in our closest living relatives, chimpanzees.
Tanya M. Smith, Manish Arora, Maya Bharatiya, Nicole Leonard, Jian‐xin Zhao, Christine Austin   +5 more
wiley   +1 more source

REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters

Science, 2020
A beneficial cocktail Since the start of the coronavirus disease 2019 (COVID-19) pandemic, considerable effort has gone into generating and characterizing neutralizing antibodies that could be used as therapeutics.
A. Baum, D. Ajithdoss, R. Copin, An-Bo Zhou, Kathryn Lanza, Nicole Negron, M. Ni, Yi Wei, K. Mohammadi, B. Musser, G. Atwal, A. Oyejide, Yenny Goez-Gazi, John W. Dutton, E. Clemmons, Hilary M Staples, Carmen Bartley, Benjamin Klaffke, Kendra J. Alfson, Michal Gazi, O. Gonzalez, E. Dick, R. Carrion, Laurent Pessaint, Maciel Porto, Anthony Cook, Renita Brown, Vaneesha Ali, J. Greenhouse, Tammy Taylor, H. Andersen, Mark G. Lewis, N. Stahl, A. Murphy, G. Yancopouloš, C. Kyratsous   +35 more
semanticscholar   +1 more source

Sustained high-level expression of human factor IX (hFIX) after liver-targeted delivery of recombinant adeno-associated virus encoding the hFIX gene in rhesus macaques [PDF]

, 2002
The feasibility, safety, and efficacy of liver-directed gene transfer was evaluated in 5 male macaques (aged 2.5 to 6.5 years) by using a recombinant adeno-associated viral (rAAV) vector (rAAV-2 CAGG-hFIX) that had previously mediated persistent ...
Hanawa, H, Ng, CYC, Mandrell, TD, Vanin, EF, Nathwani, AC, Hu, Y, Davidoff, AM, Hoffer, FA, Zhou, J, Slaughter, C, Nikanorov, A, Lozier, JN, Nienhuis, AW   +12 more
core