Results 91 to 100 of about 174,225 (258)
Defining genetic diversity of rhesus macaque Fcγ receptors with long-read RNA sequencing
Frontiers in ImmunologyFcγ receptors (FcγRs) are membrane-bound glycoproteins that bind to the fragment crystallizable (Fc) constant regions of IgG antibodies. Interactions between IgG immune complexes and FcγRs can initiate signal transduction that mediates important ...
Haleigh E. Conley +18 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Dengue virus (DENV) infection is a significant global health threat. Mosnodenvir (JNJ‐64281802) is a pan‐serotype small molecule antiviral blocking DENV replication. A Phase IIa study (NCT05048875) evaluated the antiviral activity, safety, and pharmacokinetics of mosnodenvir as prophylaxis against DENV‐3 in a controlled human infection model (CHIM).
Nele Goeyvaerts +8 more
wiley +1 more source
A rhesus macaque model of Asian-lineage Zika virus infection
Nature Communications, 2016 Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain–Barré syndrome and fetal abnormalities, but the underlying mechanisms remain poorly understood. Animal models of infection are thus urgently needed. Here we show that rhesus
D. Dudley +26 more
semanticscholar +1 more source
Cytogenetic mapping and orientation of the rhesus macaque MHC
, 2003 Applying fluorescence in situ hybridisation (FISH), six cosmid clones of rhesus macaque origin containing the genes SACM2L, RING1, BAT1 and MIC2, MIC3, MICID, and MOG of the major histocompatibility complex (MHC) were localised to the long arm of the ...
Huber, I. +5 more
core +1 more source
Identifying human-rhesus macaque gene orthologs using heterospecific SNP probes [PDF]
, 2013 We genotyped a Chinese and an Indian-origin rhesus macaque using the Affymetrix Genome-Wide Human SNP Array 6.0 and cataloged 85,473 uniquely mapping heterospecific SNPs.
Lin, Dawei +7 more
core +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
American Journal of Physical Anthropology, 2018 OBJECTIVES The impact of anthropogenic environmental changes may impose strong pressures on the behavioral flexibility of free-ranging animals. Here, we examine whether rates of interactions with humans had both a direct and indirect influence on the ...
S. Kaburu +7 more
semanticscholar +1 more source
Rhesus macaque APOBEC3G genotype frequencies.
, 2013 Rhesus macaque APOBEC3G genotype frequencies.
Michael Letko (383232) +6 more
core +1 more source
An update of the macaque testis proteome
Data in Brief, 2015 The genome sequence of rhesus macaque is a draft version with many errors and is lack of Y chromosome annotation. In the present dataset, we reanalyzed the previously published macaque testis proteome. We searched for refined protein sequences, potential
Tao Zhou +4 more
doaj +1 more source
Proteasomal degradation of TRIM5alpha during retrovirus restriction. [PDF]
PLoS Pathogens, 2008 The host protein TRIM5alpha inhibits retroviral infection at an early post-penetration stage by targeting the incoming viral capsid. While the detailed mechanism of restriction remains unclear, recent studies have implicated the activity of cellular ...
Christopher James Rold +1 more
doaj +1 more source