Results 71 to 80 of about 174,225 (258)

Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection

Advanced Science, EarlyView.
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse, Sixtine Coindre, Anne Wijkhuisen, Romain Marlin, Laure Fournier Le Ray, Juliette Pons, Melyssa Yaugel‐Novoa, Véronique Avettand‐Fenoel, Laurent Abi‐Rached, Anne‐Sophie Gallouet, Francis Relouzat, Mael Gourves, Asier Saez‐Cirion, Hisashi Arase, Gerard Zurawski, Sandra Zurawski, Nathalie Dereuddre‐Bosquet, Roger Le Grand, Stéphanie Simon, Olivier Lambotte, Benoit Favier   +20 more
wiley   +1 more source

Macaque-specific adaptations in SIV CA and Vif.

, 2016
Comparison of SIVmfa protein sequence (bolded) to related isolates of SIV and HIV-2. (A) Residues 79–100 of CA (based on SIVmac239 numbering) representing strains used in Fig 1.
Andrea Kirmaier (243219), Kevin R. McCarthy (411580), Welkin E. Johnson (243232)   +2 more
core   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Annotation and cluster analysis of spatiotemporal- and sex-related lncRNA expression in rhesus macaque brain

Genome Research, 2017
Long noncoding RNAs (lncRNAs) mediate important epigenetic regulation in a wide range of biological processes and diseases. We applied comprehensive analyses of RNA-seq and CAGE-seq (cap analysis of gene expression and sequencing) to characterize the ...
Siling Liu, Zhengbo Wang, Dong Chen, Bowen Zhang, Ren-Rong Tian, Jing Wu, Ying Zhang, Kaiyu Xu, Liu-Meng Yang, Chao Cheng, Jian Ma, Longbao Lv, Yong-Tang Zheng, Xintian Hu, Yi Zhang, Xiangting Wang, Jiali Li   +16 more
semanticscholar   +1 more source

Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques

Nature Biotechnology, 2023
A genetic method to block immune rejection of allogeneic cells is validated in monkeys. Genetic engineering of allogeneic cell therapeutics that fully prevents rejection by a recipient’s immune system would abolish the requirement for immunosuppressive ...
Xiao-Meng Hu, K. White, Ari G. Olroyd, Rowena deJesus, Antonia A. Dominguez, William E. Dowdle, Annabelle M. Friera, Young Chi, Frank Wells, Elaine Y. Chu, C. Ito, Harini Krishnapura, Surbhi Jain, Ramya Ankala, T. Mcgill, A. Lin, Kyla Egenberger, Allison Gagnon, J. M. Rukstalis, N. Hogrebe, Corie Gattis, R. Basco, J. Millman, P. Kievit, Mark M. Davis, L. Lanier, A. Connolly, T. Deuse, S. Schrepfer   +28 more
semanticscholar   +1 more source

Rhesus Macaque TRAV and TRDV genes

, 2016
TRAV and TRDV genes extracted from the rhesus macaque genome. The gene features reported include L-PART1, V-INTRON, V-EXON, V-HEPTAMER, V-SPACER, and V-NONAMER.
David M. Lewinsohn (266240), Roth, Benjamin F., Ford, Julia C., Crank, Hugh, Picker, Louis J., Benjamin F. Roth (3310326), Deborah A. Lewinsohn (363574), William Hildebrand (264375), Lewinsohn, Deborah A., McMurtrey, Curtis, Katherine B. Hammond (843986), Pradyot Dash (194289), Jeffrey J. Stanton (3310341), Hammond, Katherine B., Greenaway, Hui Yee, Bae, Joseph Y., Venturi, Vanessa, Adams, Erin J., Marielle C. Gold (363563), Legasse, Alfred W., Louis J. Picker (3140679), Hansen, Scott G., Lewinsohn, David M., Byung S. Park (347249), Shaheed Abdulhaqq (3310365), Michael K. Axthelm (359276), Gold, Marielle C., Burwitz, Benjamin J., Jonah B. Sacha (539908), Curtis McMurtrey (3310347), Abdulhaqq, Shaheed, Erin J. Adams (253263), Melanie J. Harriff (363573), David W. Morrow (3310329), Monica Kurniawan (3310344), Sobhan Roy (3310335), Roy, Sobhan, Paul G. Thomas (194304), Hildebrand, William, Joseph Y. Bae (3310359), Dash, Pradyot, Reed, Jason, S., Greene, Justin, M. (3310389), Julia C. Ford (3310362), Guangwu Xu (3310338), Thomas, Paul G., Wu, Helen L., Dang, Thurston H., Benjamin J. Burwitz (36131), Alfred W. Legasse (3140685), Hui Yee Greenaway (3310350), Xu, Guangwu, Axthelm, Michael K., Morrow, David W., Sacha, Jonah B., Greene, Justin, M., Walid Awad (3310353), Vanessa Venturi (182536), Helen L. Wu (843985), Reed, Jason, S. (3310386), Scott G. Hansen (843989), Awad, Walid, Kurniawan, Monica, Harriff, Melanie J., Stanton, Jeffrey J., Park, Byung S., Hugh Crank (3310332), Thurston H. Dang (3310356)   +67 more
core   +1 more source

Long-read structural variant discovery and targeted short read genotyping enables population scale characterization of structural variation in rhesus macaques

Genome Biology
Background Due to their close evolutionary relationship with humans, rhesus macaques are an important pre-clinical model. While genetic diversity driven by short nucleotide variation has long been studied in rhesus macaques, there is comparatively little
Karina Ray, Christina Mulch, Samuel M. Peterson, Sebastian Benjamin, Nathan Gullicksrud, Adam J. Ericsen, Eric J. Vallender, Betsy M. Ferguson, Jeffrey D. Wall, Benjamin N. Bimber   +9 more
doaj   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

Annotation and functional clustering of circRNA expression in rhesus macaque brain during aging

Cell Discovery, 2018
The abundance and function of circular RNAs (circRNAs) in mammalian brain have been reported, but their alterations in the biology of brain aging remain elusive.
Kaiyu Xu, Dong Chen, Zhengbo Wang, Jian Ma, Jian Zhou, N. Chen, Longbao Lv, Yong-Tang Zheng, Xintian Hu, Yi Zhang, Jiali Li   +10 more
semanticscholar   +1 more source

Descriptive, comparative, and functional anatomy of the facial musculature in cattle (Bos taurus)

The Anatomical Record, EarlyView.
Abstract Facial expressions can provide insight into animal emotions and pain, but no standardized system for assessing the entire facial display in cattle (Bos taurus Linnaeus) exists. The Facial Action Coding System (FACS), originally developed for humans, identifies distinct facial movements based on mimetic muscles.
Maja Söderlind, Bridget Cain, Katrina Ask, Jean‐Francois Valarcher, Elin Hernlund, Pia Haubro Andersen, Marie Rhodin   +6 more
wiley   +1 more source