Results 81 to 90 of about 30,289 (203)

Dystrophia Smolandiensis is characterized by a novel NQO1 variant and a distinct phenotype from COL17A1‐associated epithelial recurrent erosion dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer, Kristina Lagerstedt‐Robinson, Daniel Nilsson, Cilla Söderhäll, Björn Hammar, Erik Björck   +5 more
wiley   +1 more source

Nonhuman Primate Model of Oculocutaneous Albinism with TYR and OCA2 Mutations

Research, 2020
Human visual acuity is anatomically determined by the retinal fovea. The ontogenetic development of the fovea can be seriously hindered by oculocutaneous albinism (OCA), which is characterized by a disorder of melanin synthesis.
Kun-Chao Wu, Ji-Neng Lv, Hui Yang, Feng-Mei Yang, Rui Lin, Qiang Lin, Ren-Juan Shen, Jun-Bin Wang, Wen-Hua Duan, Min Hu, Jun Zhang, Zhan-Long He, Zi-Bing Jin   +12 more
doaj   +1 more source

Trace Element Patterns in Juvenile Wild Chimpanzee Dentitions

Archaeometry, EarlyView.
ABSTRACT Trace elements are used to infer mammalian early‐life diets, environmental toxins, dispersal patterns, stress histories, and weaning ages. Here, we employ laser ablation‐inductively coupled plasma‐mass spectrometry (LA‐ICP‐MS) to reveal elemental patterns in our closest living relatives, chimpanzees.
Tanya M. Smith, Manish Arora, Maya Bharatiya, Nicole Leonard, Jian‐xin Zhao, Christine Austin   +5 more
wiley   +1 more source

Brain viral reservoir seeding and neurological metabolic dysregulation in early‐life immunodeficiency virus infection

Brain Pathology, EarlyView.
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma, Robert Blair, Yao‐Zhong Liu, Xiaolei Wang, Eunice Vincent, Christopher Yu, Lara A. Doyle‐Meyers, Cissy Zhang, Ahmad Saied, Anne Le, Ronald S. Veazey, Qigui Yu, Huanbin Xu   +12 more
wiley   +1 more source

Natural Norovirus Infections in Rhesus Macaques [PDF]

Emerging Infectious Diseases, 2016
Using a recently developed real-time reverse transcription PCR, I retested 500 fecal samples from rhesus macaques collected in 2008. Previous conventional reverse transcription PCR testing identified 1 isolate of GII norovirus; retesting found GI, GII, and possible GIV noroviruses in the samples, indicating the natural circulation of noroviruses in ...
openaire   +3 more sources

Albinism in a juvenile rhesus macaque Macaca mulatta (Zimmermann 1780) from the Brahmaputra Valley of Assam, India (Primates: Cercopithecidae)

Natural History Sciences
Color aberrations are rare phenomena in wild mammals and are often associated with genetic disruptions affecting melanin production or deposition. The rhesus macaque Macaca mulatta, one of the most widespread primate species in India, has only rarely ...
Neeraj Bora, Sanghamitra Buragohain, Deep Jyoti Borah, Chiranjib Bora, Sandip Choudhury, Jyotismita Das   +5 more
doaj   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque embryonic brain histology datasets

Journal of Anatomy, EarlyView.
We introduce the MacBrain Resource Center (MBRC) Collections of rhesus macaque embryonic brain tissue. Here, we illustrate histo‐ and immunohistology from our dynamically growing Collection 6, which currently contains >10,000 zoomable and downloadable images from n = 14 male and female embryos from early to late in gestation.
Valeria Mendoza‐Silva, Emma Burke, Lucy Greene, Mikhail Rodov, Janja Kopić, Phil Barello, Yury M. Morozov, Keiko Moriya‐Ito, Chiaki Ohtaka‐Maruyama, Zeljka Krsnik, Pasko Rakic, Alvaro Duque   +11 more
wiley   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

Journal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva, Lucy Greene, Emma Burke, Cristina Canales, Julia Chocarro, Jose L. Lanciego, Khuleshwari Kurrey, Phil Barello, Aya Nusir, Nadine Kabbani, Kathleen S. Rockland, Dibyadeep Datta, Jon I. Arellano, Amy F. T. Arnsten, Yury M. Morozov, Bashir Ahmed, Zoltán Molnár, Caroline J. Zeiss, Pasko Rakic, Alvaro Duque   +19 more
wiley   +1 more source

Memory T Cells in Rhesus Macaques [PDF]

, 2010
The Rhesus macaque (Macaca mulatta) is one of the best studied species of Old World monkeys. DNA sequencing of the entire Rhesus macaque genome, completed in 2007, has demonstrated that humans and macaques share about 93% of their nucleotide sequence.
Monica, Vaccari, Genoveffa, Franchini
openaire   +2 more sources

Effective and stable gene transduction in rhesus macaque iPSCs capable of T-lineage differentiation utilizing the piggyBac system

Regenerative Therapy
Introduction: Genetically modified human induced pluripotent stem cell (iPSC)-based regenerative medicine has substantial potential in the treatment of refractory human diseases.
Masahiro Tanaka, Yoshihiro Iwamoto, Bo Wang, Eri Imai, Munehiro Yoshida, Shoichi Iriguchi, Shin Kaneko   +6 more
doaj   +1 more source