Results 151 to 160 of about 174,225 (258)
Sociability Under Anthropogenic Change: From Individual Behaviour to Population‐Level Consequences
Our review synthesises empirical and theoretical research on how anthropogenic environmental change reshapes animal social behaviour from individuals to populations. We use sociability as an individual‐level lens, distinguishing context‐dependent expression from repeatable interindividual differences and linking both to social relationships, network ...
Paulina Kowalczyk, Barbara Pietrzak
wiley +1 more source
HIV-1 replication in rhesus macaque PBMC.
Simian tropic (st) HIV-1 viral stocks encoding SIVmacVif, and either SIVmac239 CA, WT HIV-1NL4-3 CA, or the indicated mutant HIV-1 CA proteins were normalized according to reverse transcriptase activity and used to infect rhesus macaque PBMC.
Theodora Hatziioannou (220814) +4 more
core +1 more source
Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
Temporal transcriptomic dynamics in developing macaque neocortex
Despite intense research on mice, the transcriptional regulation of neocortical neurogenesis remains limited in humans and non-human primates. Cortical development in rhesus macaque is known to recapitulate multiple facets of cortical development in ...
Longjiang Xu +10 more
doaj +1 more source
GFD‐CD3, a uPAR‐targeting T‐cell engager, effectively cleared senescent cells and mitigated age‐related pathologies with a favorable safety profile under transaminase‐guided monitoring. ABSTRACT Senolytic CAR‐T cells targeting uPAR induce dose‐dependent toxicities.
Jian Deng +13 more
wiley +1 more source
The ocular surface microbiome of rhesus macaques
Background The ocular surface microbiota (OSM) is important for eye health, and variations in OSM composition have been associated with multiple diseases in humans. Studies of OSM-disease dynamics in humans are confounded by lifestyle factors.
Joelle K. Hass +10 more
doaj +1 more source
Novel rhesus macaque immunoglobulin germline genes identified by three sequencing approaches
IntroductionRhesus macaques have long been a focus of research for understanding immune responses to human pathogens due to their close phylogenetic relationship with humans.
Yicheng Guo +8 more
doaj +1 more source
ABSTRACT Introduction Natural hosts of simian immunodeficiency virus (SIV), including sooty mangabeys (SMs), maintain high viremia without progressing to AIDS and AIDS‐associated histopathogenesis. The mechanisms underlying this protection and lack of pathogenesis remain incompletely understood, particularly in relation to monocyte/macrophage ...
Caroline Soulas +7 more
wiley +1 more source
Extraction and characterization of the rhesus macaque T‐cell receptor β‐chain genes
Rhesus macaque models have been instrumental in the development and testing of vaccines before human studies and have provided fundamental insights into the determinants of immune efficacy in a variety of infectious diseases.
Douek, Daniel C. +11 more
core +1 more source
Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.
ABSTRACT Background Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra.
M. E. Hensel +4 more
wiley +1 more source

