Results 21 to 30 of about 30,289 (203)

Rhesus macaque rhadinovirus-associated disease [PDF]

Current Opinion in Virology, 2013
Rhesus macaque rhadinovirus (RRV) is a gamma-2 herpesvirus that naturally infects rhesus macaque (RM) monkeys and is closely related to human herpesvirus-8 (HHV-8)/Kaposi's sarcoma-associated herpesvirus (KSHV). Infection of immunodeficient RM induces disease in infected RM that resembles KSHV-associated pathologies.
Ryan D, Estep, Scott W, Wong
openaire   +2 more sources

Extensive prevalence and significant genetic differentiation of Blastocystis in high- and low-altitude populations of wild rhesus macaques in China

Parasites & Vectors, 2023
Background Blastocystis is a common intestinal protist with a wide range of hosts. Thus far, 38 subtypes have been identified. In recent years, wild animals have been confronted with habitat fragmentation as well as an increasing risk of zoonotic disease
Mengshi Yu, Yongfang Yao, Hongtao Xiao, Meng Xie, Ying Xiong, Shengzhi Yang, Qingyong Ni, Mingwang Zhang, Huailiang Xu   +8 more
doaj   +1 more source

Development of immortalized rhesus macaque kidney cells supporting infection with a panel of viruses.

PLoS ONE, 2023
Non-human primate (NHP)-based model systems faithfully reproduce various viral diseases including Ebola, influenza, AIDS and Zika. However, only a small number of NHP cell lines are available and generation of additional cell lines could help to refine ...
Stefanie Reiter, Sabine Gärtner, Katharina Decker, Stefan Pöhlmann, Michael Winkler   +4 more
doaj   +1 more source

Identification and characterization of the T cell receptor (TCR) repertoire of the cynomolgus macaque (Macaca Fascicularis)

BMC Genomics, 2022
Background Cynomolgus macaque (Macaca fascicularis) is an attractive animal model for the study of human disease and is extensively used in biomedical research.
Swati Jaiswal, Sarah K. Nyquist, Shayla Boyce, Tasneem Jivanjee, Samira Ibrahim, Joshua D. Bromley, G. James Gatter, Hannah Gideon, Kush Patel, Sharie Keanne Ganchua, Bonnie Berger, Sarah M. Fortune, JoAnne L. Flynn, Alex K. Shalek, Samuel M. Behar   +14 more
doaj   +1 more source

The mosaic of KIR haplotypes in rhesus macaques [PDF]

Immunogenetics, 2010
To further refine and improve biomedical research in rhesus macaques, it is necessary to increase our knowledge concerning both the degree of allelic variation (polymorphism) and diversity (gene copy number variation) in the killer cell immunoglobulin-like receptor (KIR) gene cluster.
Blokhuis, J.H., van der Wiel, M.K., Doxiadis, G.G.M., Bontrop, R.E.   +3 more
openaire   +3 more sources

Rapid Transduction and Expansion of Transduced T Cells with Maintenance of Central Memory Populations

Molecular Therapy: Methods & Clinical Development, 2020
Chimeric antigen receptor (CAR)-T cells show great promise in treating cancers and viral infections. However, most protocols developed to expand T cells require relatively long periods of time in culture, potentially leading to progression toward ...
Mary S. Pampusch, Kumudhini Preethi Haran, Geoffrey T. Hart, Eva G. Rakasz, Aaron K. Rendahl, Edward A. Berger, Elizabeth Connick, Pamela J. Skinner   +7 more
doaj   +1 more source

The rhesus macaque is three times as diverse but more closely equivalent in damaging coding variation as compared to the human

BMC Genetics, 2012
Background As a model organism in biomedicine, the rhesus macaque (Macaca mulatta) is the most widely used nonhuman primate. Although a draft genome sequence was completed in 2007, there has been no systematic genome-wide comparison of genetic variation ...
Yuan Qiaoping, Zhou Zhifeng, Lindell Stephen G, Higley J, Ferguson Betsy, Thompson Robert C, Lopez Juan F, Suomi Stephen J, Baghal Basel, Baker Maggie, Mash Deborah C, Barr Christina S, Goldman David   +12 more
doaj   +1 more source

Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche

Nature Communications, 2018
Human embryonic stem cells can be differentiated in vitro into primordial germ cell-like cells (PGCLCs) that resemble early primordial germ cells (PGCs). Here the authors transplant PGCLCs generated from rhesus macaque iPSCs into mouse and rhesus macaque
Enrique Sosa, Di Chen, Ernesto J. Rojas, Jon D. Hennebold, Karen A. Peters, Zhuang Wu, Truong N. Lam, Jennifer M. Mitchell, Meena Sukhwani, Ramesh C. Tailor, Marvin L. Meistrich, Kyle E. Orwig, Gunapala Shetty, Amander T. Clark   +13 more
doaj   +1 more source

An integration-free, virus-free rhesus macaque induced pluripotent stem cell line (riPSC90) from embryonic fibroblasts

Stem Cell Research, 2017
The rhesus macaque induced pluripotent stem cell (riPSC) line, UCLAi090-A (riPSC90), was generated from rhesus embryonic fibroblast (REF) cells called REF90.
Enrique Sosa, Rachel Kim, Ernesto J. Rojas, Linzi Hosohama, Jon D. Hennebold, Kyle E. Orwig, Amander T. Clark   +6 more
doaj   +1 more source

The Subcortical Atlas of the Rhesus Macaque (SARM) for neuroimaging

NeuroImage, 2021
Digitized neuroanatomical atlases that can be overlaid onto functional data are crucial for localizing brain structures and analyzing functional networks identified by neuroimaging techniques.
Renée Hartig, Daniel Glen, Benjamin Jung, Nikos K. Logothetis, George Paxinos, Eduardo A. Garza-Villarreal, Adam Messinger, Henry C. Evrard   +7 more
doaj   +1 more source