Results 31 to 40 of about 43,519 (198)

The mosaic of KIR haplotypes in rhesus macaques [PDF]

Immunogenetics, 2010
To further refine and improve biomedical research in rhesus macaques, it is necessary to increase our knowledge concerning both the degree of allelic variation (polymorphism) and diversity (gene copy number variation) in the killer cell immunoglobulin-like receptor (KIR) gene cluster.
Blokhuis, J.H., van der Wiel, M.K., Doxiadis, G.G.M., Bontrop, R.E.   +3 more
openaire   +3 more sources

The rhesus macaque as a success story of the Anthropocene

eLife, 2022
Of all the non-human primate species studied by researchers, the rhesus macaque ( Macaca mulatta ) is likely the most widely used across biological disciplines. Rhesus macaques have thrived during the Anthropocene and now have the largest natural range of any non-human primate.
Eve B. Cooper, Lauren J. N. Brent, Noah Snyder‐Mackler, Mewa Singh, Asmita Sengupta, Sunil Khatiwada, Suchinda Malaivijitnond, Qihai Zhou, James P. Higham   +8 more
openaire   +4 more sources

The rhesus macaque is three times as diverse but more closely equivalent in damaging coding variation as compared to the human

BMC Genetics, 2012
Background As a model organism in biomedicine, the rhesus macaque (Macaca mulatta) is the most widely used nonhuman primate. Although a draft genome sequence was completed in 2007, there has been no systematic genome-wide comparison of genetic variation ...
Yuan Qiaoping, Zhou Zhifeng, Lindell Stephen G, Higley J, Ferguson Betsy, Thompson Robert C, Lopez Juan F, Suomi Stephen J, Baghal Basel, Baker Maggie, Mash Deborah C, Barr Christina S, Goldman David   +12 more
doaj   +1 more source

Rapid Transduction and Expansion of Transduced T Cells with Maintenance of Central Memory Populations

Molecular Therapy: Methods & Clinical Development, 2020
Chimeric antigen receptor (CAR)-T cells show great promise in treating cancers and viral infections. However, most protocols developed to expand T cells require relatively long periods of time in culture, potentially leading to progression toward ...
Mary S. Pampusch, Kumudhini Preethi Haran, Geoffrey T. Hart, Eva G. Rakasz, Aaron K. Rendahl, Edward A. Berger, Elizabeth Connick, Pamela J. Skinner   +7 more
doaj   +1 more source

Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche

Nature Communications, 2018
Human embryonic stem cells can be differentiated in vitro into primordial germ cell-like cells (PGCLCs) that resemble early primordial germ cells (PGCs). Here the authors transplant PGCLCs generated from rhesus macaque iPSCs into mouse and rhesus macaque
Enrique Sosa, Di Chen, Ernesto J. Rojas, Jon D. Hennebold, Karen A. Peters, Zhuang Wu, Truong N. Lam, Jennifer M. Mitchell, Meena Sukhwani, Ramesh C. Tailor, Marvin L. Meistrich, Kyle E. Orwig, Gunapala Shetty, Amander T. Clark   +13 more
doaj   +1 more source

An integration-free, virus-free rhesus macaque induced pluripotent stem cell line (riPSC90) from embryonic fibroblasts

Stem Cell Research, 2017
The rhesus macaque induced pluripotent stem cell (riPSC) line, UCLAi090-A (riPSC90), was generated from rhesus embryonic fibroblast (REF) cells called REF90.
Enrique Sosa, Rachel Kim, Ernesto J. Rojas, Linzi Hosohama, Jon D. Hennebold, Kyle E. Orwig, Amander T. Clark   +6 more
doaj   +1 more source

The Subcortical Atlas of the Rhesus Macaque (SARM) for neuroimaging

NeuroImage, 2021
Digitized neuroanatomical atlases that can be overlaid onto functional data are crucial for localizing brain structures and analyzing functional networks identified by neuroimaging techniques.
Renée Hartig, Daniel Glen, Benjamin Jung, Nikos K. Logothetis, George Paxinos, Eduardo A. Garza-Villarreal, Adam Messinger, Henry C. Evrard   +7 more
doaj   +1 more source

Hierarchical organization of rhesus macaque behavior [PDF]

Oxford Open Neuroscience, 2021
ABSTRACT Primatologists, psychologists and neuroscientists have long hypothesized that primate behavior is highly structured. However, delineating that structure has been impossible due to the difficulties of precision behavioral tracking.
Benjamin Voloh, Benjamin R. Eisenreich, David J-N. Maisson, R. Becket Ebitz, Hyun Soo Park, Benjamin Y. Hayden, Jan Zimmermann   +6 more
openaire   +2 more sources

The statistical neuroanatomy of frontal networks in the macaque [PDF]

, 2008
We were interested in gaining insight into the functional properties of frontal networks based upon their anatomical inputs. We took a neuroinformatics approach, carrying out maximum likelihood hierarchical cluster analysis on 25 frontal cortical areas ...
Averbeck Bruno B., Averbeck, BB, Seo, M, Bruno B Averbeck, Moonsang Seo, Seo Moonsang, Bruno B. Averbeck   +6 more
core   +2 more sources

Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity [PDF]

, 2010
TRIMCyps are anti-retroviral proteins that have arisen independently in New World and Old World primates. All TRIMCyps comprise a CypA domain fused to the tripartite domains of TRIM5α but they have distinct lentiviral specificities, conferring HIV-1 ...
Ylinen, L.M.J., Ylinen, LMJ, Greg J Towers, Hué, S., Marzetta, F, Laura M J Ylinen, Flavia Marzetta, Rose, NJ, Towers, G.J., Rose, N.J., Marzetta, Flavia, Hué, Stéphane, Leo C James, Rose, Nicola J, Price, A.J., Nicola J Rose, Amanda J. Price, James, L.C., Stéphane Hué, Price, Amanda J, Rasaiyaah, Jane, Marzetta, F., Towers, Greg J, Rasaiyaah, J., Laura M. J. Ylinen, Amanda J Price, Ylinen, Laura MJ, Jane Rasaiyaah, Greg J. Towers, Price, AJ, James, LC, Rasaiyaah, J, Nicola J. Rose, James, Leo C, Towers, GJ, Hue, S, Leo C. James   +36 more
core   +1 more source