Results 91 to 100 of about 29,586 (180)

Interaction between extracellular matrix molecules and microbial pathogens: evidence for the missing link in autoimmunity with rheumatoid arthritis as a disease model. [PDF]

open access: yes, 2014
Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation followed by tissue rebuilding or fibrosis. A failure by the body to regulate inflammation effectively is one of the hallmarks of RA.
Bella   +31 more
core   +3 more sources

Alpine flora of Kashmir Himalaya: floristic assessment, life history traits and threat status

open access: yesNordic Journal of Botany, EarlyView.
Alpine ecosystems in the Himalaya are considered to be at a higher risk to anthropogenic global change drivers. The Kashmir Himalaya, located in the north‐western side of the Himalayan biodiversity hotspot, harbors a diverse alpine flora, which remains systematically little investigated.
Bilal A. Rasray   +5 more
wiley   +1 more source

Biochemical Evaluation of Withania Somnifera Root Powder on Adjuvant-Induced Arthritis in Rats [PDF]

open access: yes, 2015
The present investigation was carried out to evaluate the biochemical effect of Withania somnifera Linn. Solanaceae, commonly known as ashwagandha on adjuvant induced arthritic rats.
Rasool, M. (Mahaboobkhan)   +1 more
core  

The shared benefits of fallen fruits: A novel mechanism stabilizing a nursery pollination mutualism between Sambucus and kateretid beetles

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Understanding how cooperative interactions remain stable matters for biodiversity because many plants rely on specialist insects that can also impose reproductive costs. We studied the interaction between Sambucus sieboldiana and seed‐consuming Heterhelus beetles through detailed field observations and pollination experiments.
Suzu Kawashima   +3 more
wiley   +1 more source

Podiatry services for patients with arthritis: an unmet need [PDF]

open access: yes, 2010
Foot problems are extremely common in patients with rheumatoid arthritis (RA). There is ample evidence that foot pain, either alone or as a comorbidity, contributes significantly to disability.
Chapman, J   +4 more
core   +1 more source

What is new in the management of rapidly progressive glomerulonephritis? [PDF]

open access: yes, 2015
Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
Greenhall, GHB, Salama, AD
core   +1 more source

Benzalacetone Synthase

open access: yesFrontiers in Plant Science, 2012
Benzalacetone synthase, from the medicinal plant Rheum palmatum (Polygonaceae) (RpBAS), is a plant-specific chalcone synthase (CHS) superfamily of type III polyketide synthase (PKS).
Ikuro eAbe
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

open access: yesThe FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova   +5 more
wiley   +1 more source

Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao   +6 more
wiley   +1 more source

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