Results 91 to 100 of about 29,586 (180)
Interaction between extracellular matrix molecules and microbial pathogens: evidence for the missing link in autoimmunity with rheumatoid arthritis as a disease model. [PDF]
Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation followed by tissue rebuilding or fibrosis. A failure by the body to regulate inflammation effectively is one of the hallmarks of RA.
Bella +31 more
core +3 more sources
Alpine flora of Kashmir Himalaya: floristic assessment, life history traits and threat status
Alpine ecosystems in the Himalaya are considered to be at a higher risk to anthropogenic global change drivers. The Kashmir Himalaya, located in the north‐western side of the Himalayan biodiversity hotspot, harbors a diverse alpine flora, which remains systematically little investigated.
Bilal A. Rasray +5 more
wiley +1 more source
Biochemical Evaluation of Withania Somnifera Root Powder on Adjuvant-Induced Arthritis in Rats [PDF]
The present investigation was carried out to evaluate the biochemical effect of Withania somnifera Linn. Solanaceae, commonly known as ashwagandha on adjuvant induced arthritic rats.
Rasool, M. (Mahaboobkhan) +1 more
core
Understanding how cooperative interactions remain stable matters for biodiversity because many plants rely on specialist insects that can also impose reproductive costs. We studied the interaction between Sambucus sieboldiana and seed‐consuming Heterhelus beetles through detailed field observations and pollination experiments.
Suzu Kawashima +3 more
wiley +1 more source
Podiatry services for patients with arthritis: an unmet need [PDF]
Foot problems are extremely common in patients with rheumatoid arthritis (RA). There is ample evidence that foot pain, either alone or as a comorbidity, contributes significantly to disability.
Chapman, J +4 more
core +1 more source
What is new in the management of rapidly progressive glomerulonephritis? [PDF]
Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
Greenhall, GHB, Salama, AD
core +1 more source
Benzalacetone synthase, from the medicinal plant Rheum palmatum (Polygonaceae) (RpBAS), is a plant-specific chalcone synthase (CHS) superfamily of type III polyketide synthase (PKS).
Ikuro eAbe
doaj +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova +5 more
wiley +1 more source
Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao +6 more
wiley +1 more source

