Results 181 to 190 of about 156,559 (321)

Rheumatic heart disease in identical twins [PDF]

, 1941

openalex   +1 more source

Hypothalamus Regulates Anabolic Metabolism of Articular Cartilage Superficial Chondrocytes through PGE2 Skeletal Interoception

Advanced Science, EarlyView.
Hypothalamus sympathetic norepinephrine inhibits regeneration of articular cartilage. Mechanical loading on bone during animal activity elevates PGE2 skeletal interoception to promote an anabolic renewal of the superficial membrane by downregulation of norepinephrine for articular cartilage proper thickness and integrity.
Ziyi Wang, Xuequan Han, Jiawen Xu, Weixin Zhang, Kalp Patel, Jinjian Zheng, Mei Wan, Junying Zheng, Xu Cao   +8 more
wiley   +1 more source

Discussion on Neurological Aspects of Rheumatic Diseases [PDF]

, 1949

openalex   +1 more source

Bioengineering Platelets Presenting PD‐L1, Galectin‐9 and BTLA to Ameliorate Type 1 Diabetes

Advanced Science, EarlyView.
IFN‐γ‐primed platelets enriched with immunosuppressive ligands (PD‐L1, PD‐L2, BTLA, and Gal‐9) are shown to induce T cell exhaustion and apoptosis, preserving β‐cell function and preventing hyperglycemia progression in type 1 diabetes. IFN‐γ platelets also promote Treg expansion, macrophage polarization, and β‐cell proliferation, offering a promising ...
Yumeng Ma, Fanqiang Meng, Zhongda Lin, Yanjun Chen, Tianyu Lan, Zhaoxin Yang, Rui Diao, Xiaozhou Zhang, Qi Chen, Chi Zhang, Yishi Tian, Chanjuan Li, Wenli Fang, Xin Liang, Xudong Zhang   +14 more
wiley   +1 more source

Bacterial Capture‐Killing Capsules with Remodeling Bone Immune Microenvironment for the Effective Treatment of Osteomyelitis

Advanced Science, EarlyView.
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang, Chang Shu, Chengwei Xu, Xingjie Zan, Shaoyin Wei, Chenglong Wang, Lianxin Li   +6 more
wiley   +1 more source

Heberden Oration, 1963 : The Epidemiology of Rheumatic Diseases [PDF]

, 1964
J. H. Kellgren
openalex   +1 more source

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

Advanced Science, EarlyView.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo, Yingsen Tang, Ling Zeng, Xiaomei You, Siweier Luo, Yufei Du, Le Wang, Liangchun Wang, Jianchuan Wang, Jinjin Chen, Yiming Zhou   +10 more
wiley   +1 more source

Protocol for the MERINO study: A randomized placebo-controlled trial assessing the efficacy, safety, and cost-effectiveness of methotrexate in people with erosive hand osteoarthritis

Osteoarthritis and Cartilage Open
Objective: Previous studies on the efficacy of methotrexate in people with hand osteoarthritis (OA) have shown conflicting results. The MERINO trial aims to investigate the efficacy and safety of methotrexate in people with painful inflammatory erosive ...
Alexander Mathiessen, Line Gaundal, Joseph Sexton, Dag Sjølie, Pernille Steen Pettersen, Barbara Slatkowsky-Christensen, Ida Kristin Haugen   +6 more
doaj  

The Impact of Menopause on Autoimmune and Rheumatic Diseases. [PDF]

Clin Rev Allergy Immunol
Motta F, Di Simone N, Selmi C.
europepmc   +1 more source

Necropsy study of endomyocardial fibrosis and rheumatic heart disease in Uganda 1950-1965. [PDF]

, 1968
A. G. Shaper, M. S. R. Hutt, Ruth M. Coles   +2 more
openalex   +1 more source