Results 11 to 20 of about 9,651,090 (393)

Epigentics in rheumatic diseases [PDF]

Zeitschrift fur Rheumatologie, 2011
The human genome comprises approximately 30000 genes needed for the formation and function of approximately 1 Million proteins in the human body. Differentiation leads to the deactivation of genes that are not needed in the specific tissues or cells.
Gay, S, Jüngel, A
core   +4 more sources

Rheumatic diseases in Africa [PDF]

Nature Reviews Rheumatology, 2021
Historically, rheumatic diseases have not received much attention in Africa, particularly in sub-Saharan Africa, possibly owing to a focus on the overwhelming incidence of infectious diseases and the decreased life span of the general population in this ...
O. Adelowo, G. Mody, M. Tikly, Omondi G Oyoo, S. Slimani   +4 more
semanticscholar   +3 more sources

Autoimmune Rheumatic Diseases [PDF]

BioMed Research International, 2014
The term autoimmune rheumatic diseases (ARDs) encompasses a heterogeneous group of conditions characterized by joint involvement along with a wide spectrum of systemic manifestations. The most common ARDs are rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Nevertheless, all these conditions share similar pathophysiological mechanisms [
Anaya, Juan Manuel, Shoenfeld, Yehuda, Buttgereit, Frank, González-Gay Mantecón, Miguel Ángel   +3 more
openaire   +5 more sources

Increased risk of herpes zoster with tofacitinib treatment in Korean patients with rheumatoid arthritis: a single-center prospective study

Scientific Reports, 2023
We aimed to determine the risk of herpes zoster (HZ) in Korean rheumatoid arthritis (RA) patients on tofacitinib compared with tumor necrosis factor inhibitor (TNFi) treatment.
Yeo-Jin Song, Soo-Kyung Cho, Hyoungyoung Kim, Hye Won Kim, Eunwoo Nam, Ja-Young Jeon, Hyun-Jeong Yoo, Chan-Bum Choi, Tae-Hwan Kim, Jae-Bum Jun, Sang-Cheol Bae, Dae Hyun Yoo, Yoon-Kyoung Sung   +12 more
doaj   +1 more source

Elderly onset atypical Lemierre’s syndrome concurrent with a rheumatoid vasculitis sacral ulcer infection: a case report

BMC Infectious Diseases, 2023
Background Typical Lemierre’s syndrome is usually secondary to an oropharyngeal infection. Recently, several cases following a primary infection site other than the oropharynx have been reported as atypical Lemierre’s syndrome; although, these primary ...
Koji Mishima, Kazunobu Aoki, Yusuke Shirai, Hiroshi Aritomo, Maiko Iwasaka, Masakazu Katsura, Tomofumi Tatsutani, Hiroko Ikeuchi, Kensuke Oryoji, Shinichi Mizuki   +9 more
doaj   +1 more source

Low-Dose IL-2 Therapy in Autoimmune and Rheumatic Diseases

Frontiers in Immunology, 2021
Regulatory T cells (Treg) are crucial for the maintenance of peripheral tolerance and for the control of ongoing inflammation and autoimmunity. The cytokine interleukin-2 (IL-2) is essentially required for the growth and survival of Treg in the ...
H. Grasshoff, Sara Comdühr, Luisa R. Monne, A. Müller, P. Lamprecht, G. Riemekasten, J. Humrich   +6 more
semanticscholar   +1 more source

Enabling personal recovery from fibromyalgia – theoretical rationale, content and meaning of a person-centred, recovery-oriented programme

BMC Health Services Research, 2021
Background Fibromyalgia (FM) is a contested, chronic widespread pain syndrome on which recommended therapies have short-lasting, moderate effects. Nevertheless, some patients become symptom-free, and their recovery experiences inspired us to develop a ...
Anne Marit Mengshoel, Åse Skarbø, Elisabeth Hasselknippe, Tamara Petterson, Nina Linnea Brandsar, Ellen Askmann, Ragnhild Ildstad, Lena Løseth, Merja Helena Sallinen   +8 more
doaj   +1 more source

Early experience of COVID-19 vaccination in adults with systemic rheumatic diseases: results from the COVID-19 Global Rheumatology Alliance Vaccine Survey

RMD Open, 2021
Background We describe the early experiences of adults with systemic rheumatic disease who received the COVID-19 vaccine. Methods From 2 April to 30 April 2021, we conducted an online, international survey of adults with systemic rheumatic disease who ...
S. Sattui, J. Liew, K. Kennedy, E. Sirotich, M. Putman, Tarin T Moni, A. Akpabio, D. Alpízar-Rodríguez, F. Berenbaum, I. Buliņa, R. Conway, A. Singh, Eimear Duff, K. Durrant, T. Gheita, C. Hill, Richard A Howard, B. Hoyer, E. Hsieh, Lina El Kibbi, Adam Kilian, A. H. Kim, D. Liew, Chieh Lo, B. Miller, S. Mingolla, M. Nudel, C. Palmerlee, J. Singh, Namrata Singh, M. Ugarte-Gil, J. Wallace, Kristen J Young, S. Bhana, W. Costello, R. Grainger, P. Machado, P. Robinson, P. Sufka, Z. Wallace, J. Yazdany, Carly Harrison, M. Larché, M. Levine, G. Foster, L. Thabane, L. Rider, J. Hausmann, J. Simard, J. Sparks   +49 more
semanticscholar   +1 more source

IgG anti-hinge antibodies against IgG4 F(ab’)2 fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating immunogenic hinge epitopes

Arthritis Research & Therapy, 2020
Background Pepsin agglutinators, discovered over 50 years ago, have been recently referred to as anti-hinge antibodies (AHAs) because of their reaction with the IgG hinge epitope.
Toshiyuki Ota, Shun-ichiro Ota, Ayumi Uchino, Shuji Nagano   +3 more
doaj   +1 more source

Late Onset Dipeptidyl Peptidase -4 Inhibitor Associated Seronegative Rheumatoid Arthritis

Journal of Nepal Health Research Council, 2021
Drug-induced arthritis is not an uncommon scenario. DPP-4 inhibitors could potentially cause adverse-events mediated by cytokine-induced inflammation leading to arthritis. The activity of the DPP-4 enzyme could be inversely related to the development of
Binit Vaidya, Bhojraj Adhikari, Manisha Bhochhibhoya, Shweta Nakarmi   +3 more
doaj   +1 more source