Results 41 to 50 of about 2,245,112 (263)

DAS28-ESR may underestimate disease activity in rheumatoid arthritis patients with nonalcoholic fatty liver disease: a retrospective cohort study

Arthritis Research & Therapy
Background Although approximately one-third of patients with rheumatoid arthritis (RA) have comorbid nonalcoholic fatty liver disease (NAFLD), the clinical characteristics of these patients remain unclear.
Yutaka Shinkawa, Masao Tanaka, Tomoya Nakajima, Masashi Taniguchi, Kyosuke Fukumori, Kayo McCracken, Mori Masato, Tomomi Sato-Nakamura, Takuji Nakamura, Shinji Hirose, Akio Morinobu, Hisanori Umehara   +11 more
doaj   +1 more source

Adjunct role of potassium-rich vegetarian diet and a novel potassium food supplement to improve pain in chronic rheumatoid arthritis on supervised standard care: a randomised controlled study

BMJ Nutrition, Prevention & Health
Introduction An earlier food survey showed dietary potassium deficiency in rheumatoid arthritis (RA).Objective To evaluate an adjunct role of oral potassium to reduce joint pain in RA.Methods 172 consenting eligible symptomatic patients (median duration ...
Arvind Chopra, Manjit Saluja, Toktam Kianifard, Sanjeev Sarmukaddam, Anuradha Venugopalan   +4 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Effectiveness of bazedoxifene in preventing glucocorticoid-induced bone loss in rheumatoid arthritis patients

Arthritis Research & Therapy, 2021
Objective To evaluate the effectiveness of bazedoxifene in preventing bone loss in patients with rheumatoid arthritis (RA) receiving low-dose glucocorticoids (GCs).
Soo-Kyung Cho, Hyoungyoung Kim, Jiyoung Lee, Eunwoo Nam, Seunghun Lee, Yun Young Choi, Yoon-Kyoung Sung   +6 more
doaj   +1 more source

Autoimmune polyendocrine syndromes associated with autoimmune rheumatic diseases

, 2023
Autoimmune polyendocrine syndromes (APSs), also called autoimmune polyglandular syndromes, are a group of autoimmune diseases characterized by the co-occurrence of dysfunctions of several (at least two) endocrine glands.
Katarzyna Suchta, Małgorzata Stasiek, Katarzyna Jankowska, Piotr Dudek   +3 more
core   +1 more source

Rheumatic Diseases: Pathophysiology, Targeted Therapy, Focus on Vascular and Pulmonary Manifestations [PDF]

, 2022
This book aims to summarize the latest advances in the rheumatic diseases, particularly regarding their pathophysiology and targeted therapy, with a focus on the recent efforts of vascular and pulmonary manifestations in order to anticipate new and ...
Salton, Francesco, Confalonieri, Paola, Ruaro, Barbara   +2 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Rheumatic heart disease and acute rheumatic fever in Australia: 1996-2011 [PDF]

, 2013
Acute rheumatic fever (ARF) is rare in most developed countries, but rates among Aboriginal and Torres Strait Islander people are among the highest in the world based on available data. Rheumatic heart disease (RHD), which can be prevented by adequate

core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

IL-17A induces osteoblast differentiation by activating JAK2/STAT3 in ankylosing spondylitis

Arthritis Research & Therapy, 2018
Background IL-17A has recently emerged as a potential target that regulates the extensive inflammation and abnormal bone formation observed in ankylosing spondylitis (AS). Blocking IL-17A is expected to inhibit bony ankylosis.
Sungsin Jo, Sung Eun Wang, Young Lim Lee, Suman Kang, Bitnara Lee, Jinil Han, Il-Hoon Sung, Ye-Soo Park, Sang-Cheol Bae, Tae-Hwan Kim   +9 more
doaj   +1 more source